532 nm长脉冲Nd:YAG激光(Versapulse)治疗腿部蜘蛛静脉。

T. McMeekin
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引用次数: 20

摘要

背景与目的先前的研究表明,使用532 nm的长脉冲倍频YAG激光可以改善腿部毛细血管扩张。接下来的研究进行了更长时间的随访,以确定这种激光的有效性和对直径小于1mm的下肢毛细血管扩张进行一次治疗的副作用发生率。材料与方法10例皮肤I-III型患者在18个治疗部位分别接受单次治疗。在每条血管上使用一到三次,重复频率为2hz。比较了12 J/cm2和16 J/cm2两种能量影响。患者随访1年,并拍摄随访照片,评估血管清除率和副作用的百分比。结果:总体而言,44%的患者在使用532 nm倍频Nd:YAG激光的单次治疗后清除率大于50%。较高的16 J/cm2比较低的12 J/cm2具有更好的响应。与12 J/cm2组相比,16 J/cm2组的副作用更明显。大约94%的患者有色素沉着,需要长达6个月的时间来解决。1例以16 J/cm2治疗的患者出现水疱、结痂和瘢痕,持续1年。从6个月到1年,在三分之一的治疗地点有进一步的改善。结论532 nm长脉冲Nd:YAG激光加冷冻蓝宝石尖端可治疗直径0.5 ~ 1.0 mm的腿部毛细血管扩张,单次治疗有44%的部位清除率大于50%。16 J/cm2的影响越大,清除率越高,但副作用也越大,包括持续1年的萎缩性瘢痕。在6个月至1年的随访中观察到进一步的临床改善。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Treatment of spider veins of the leg using a long-pulsed Nd:YAG laser (Versapulse) at 532 nm.
BACKGROUND AND OBJECTIVE Prior studies have shown improvement in leg telangiectasias using a long pulse, frequency-doubled nd:YAG laser at 532 nm. The following study, with longer follow-up, was undertaken to determine the effectiveness of this laser and incidence of side-effects from a single treatment for lower extremity telangiectasia of less than 1 mm in diameter. MATERIALS AND METHODS Ten patients of skin types I-III received a single treatment on each of 18 treatment sites. One to three passes were used on each vessel with a repetition rate of 2 Hz. Two energy fluences of 12 J/cm2 and 16 J/cm2 were compared. Patients were followed for 1 year with follow-up photographs taken, from which the percentage of vessel clearance and side-effects were rated. RESULTS Overall, 44% of patients had a greater than 50% clearance from a single treatment using the frequency-doubled Nd:YAG laser at 532 nm. The higher fluence of 16 J/cm2 showed a better response than the lower fluence of 12 J/cm2. Side-effects were more marked and were seen in more patients treated at 16 J/cm2 than at the 12 J/cm2 setting. Some 94% of patients had hyperpigmentation that took up to 6 months to resolve. One patient treated at 16 J/cm2 experienced blisters, crusts and scarring, which persisted for 1 year. There was further improvement from 6 months to 1 year in one-third of the treatment sites. CONCLUSION The long-pulsed Nd:YAG laser at 532 nm with a chilled sapphire tip can treat leg telangiectasias of 0.5 to 1.0 mm in diameter with greater than 50% clearance at 44% of sites with a single treatment. Higher fluences of 16 J/cm2 demonstrated a greater clearance, but also greater adverse effects, including atrophic scarring persisting for 1 year. Further clinical improvement was seen at 6-month to 1-year follow-ups.
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