强脉冲光源下真皮重塑后新胶原蛋白的形成

D. Goldberg
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引用次数: 147

摘要

背景:激光表面置换治疗面部潮癣传统上涉及烧蚀方法及其相关并发症和局限性。最近,采用非消融方法可以改善心律和重塑皮肤。这种激光诱导的重塑可能与新的真皮胶原形成的证据有关。目的:本研究的目的是评估非激光强脉冲光源真皮重塑后的组织学变化。方法:5例患者在强脉冲光源下进行了4次真皮重塑。所有患者在最终治疗后6个月接受了预处理活检和第二次活检。最终治疗后6个月,活检评估新胶原形成的组织学证据。结果:所有患者均表现出新的上乳头真皮胶原形成的组织学证据。结论:强脉冲光源下的真皮重塑可导致新胶原形成的组织学证据,并伴有相关的临床改善。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
New collagen formation after dermal remodeling with an intense pulsed light source
BACKGROUND : Laser resurfacing in the treatment of facial rhytides has traditionally involved ablative methods with their associated complications and limitations. More recently, rhytid improvement and dermal remodeling has been seen with non-ablative approaches. Such laser-induced remodeling may be associated with evidence of new dermal collagen formation. OBJECTIVE : The aim of this study was to evaluate the histologic changes seen after dermal remodeling with a non-laser intense pulsed light source. METHODS : Five patients underwent four sessions of dermal remodeling with an intense pulsed light source. All patients received a pretreatment biopsy and a second biopsy 6 months after the final treatment. Biopsies were evaluated for histologic evidence of new collagen formation 6 months after the final treatment. RESULTS : All patients showed histologic evidence of new upper papillary dermal collagen formation. CONCLUSION : Dermal remodeling with an intense pulsed light source can lead to histologic evidence of new collagen formation with associated clinical improvement.
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