长期护理机构的尿路感染

Lindsay E. Nicolle MD, FRCPC
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引用次数: 6

摘要

无症状菌尿和脓尿在长期护理人群中普遍存在。对长期护理机构的居民进行尿路感染的最佳管理需要了解该环境中感染的独特特征,并对每位居民的每一次潜在尿路感染进行批判性评估。方法对长期护理机构中尿路感染的相关知识和建议进行非结构化回顾。结果泌尿系感染是长期护理机构住院患者第二大常见感染。对于没有长期留置导尿管的居民,急性、局部、泌尿生殖系统症状应该存在,以支持症状性感染的临床诊断。在对这些设施的抗菌药物使用情况的回顾中,一致观察到不适当的抗菌药物用于尿路感染,特别是治疗无症状的细菌尿和预防尿路感染。改善治疗的管理方法包括在症状可疑或诊断不明确时进行观察和重新评估,限制慢性留置管的使用,以及早期发现留置管阻塞等并发症。结论临床诊断的不准确和无症状菌尿的高发意味着这些感染被过度诊断和过度治疗,导致过量使用抗菌药物的不良事件。需要在长期护理机构中制定抗菌素管理规划,以改善这一适应症的抗菌素使用。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Urinary tract infection in long-term care facilities

Introduction

Asymptomatic bacteriuria and pyuria are pervasive in the long-term care population. Optimal management of urinary infection for residents of long-term care facilities requires knowledge of the unique features of the infection in this setting, together with critical evaluation of each episode of potential urinary infection in the individual resident.

Method

A non-structured review of current knowledge and recommendations relevant to urinary infection in long-term care facilities.

Results

Urinary infection is the second most common infection occurring in long-term care facility residents. For residents without chronic indwelling catheters, acute, localising, genitourinary symptoms should be present to support a clinical diagnosis of symptomatic infection. Inappropriate antimicrobial use for urinary tract infection, particularly treatment of asymptomatic bacteriuria and prophylaxis of urinary infection, is a consistent observation in reviews of antimicrobial use in these facilities. Management approaches to improve treatment include observation and reassessment when symptoms are questionable or the diagnosis is unclear, limiting the use of chronic indwelling catheters, and early identification of complications, such as obstruction, of indwelling catheters.

Conclusions

Clinical diagnostic imprecision and a high prevalence of asymptomatic bacteriuria means these infections are overdiagnosed and overtreated, leading to adverse events from excess antimicrobial use. Antimicrobial stewardship programs to improve antimicrobial use for this indication need to be developed in long-term care facilities.

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