The Relationship of Gastrin Levels with Obesity Anthropometrics, Lipid, Glucose, and Insulin Levels in Children and Adolescents with Obesity

Abstract The aim of the study was to compare the gastrin levels in obese and healthy children and to investigate the relationship of gastrin with obesity anthropometrics, lipid, and baseline insulin levels, and oral glucose tolerance test scores. Gastrin was significantly lower in the obese group compared with the control group (p > 0.001). Gastrin level displayed a negative correlation with body weight, body weight standard deviation, and insulin levels in oral glucose tolerance test at 120 minutes, a positive correlation with glycohemoglobin A1c.The results revealed that there is a significant difference between the gastrin levels in obese and healthy children.