颈椎疼痛与小关节有关

Kenneth D. Candido MD, Bryant England MD
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引用次数: 1

摘要

颈部疼痛是一种常见的诊断症状,其终生患病率在65%至80%之间。了解颈椎小关节在颈椎疼痛病因学中的作用,对于为患有退行性和创伤后颈部疼痛的个体提供持续的疼痛缓解至关重要。研究表明,大约60%遭受鞭打型追尾机动车碰撞的患者会有单独由小关节引起的疼痛,或与颈椎间盘联合引起的疼痛。了解这些疼痛状况发展的解剖学基础包括了解每个颈椎小关节的双重重叠神经支配,这些神经支配来自关节处和关节上方的水平。内侧支神经支配关节;通过头半棘肌的肌腱紧紧地附着在关节柱上;并且可以使用局部麻醉神经阻滞,然后使用射频(RF)程序进行治疗,以获得长期的益处。小关节内的神经含有改良的伤害感受器,包括沉默的伤害感受器、低阈值的机械感受器和机械敏感的伤害感受器。关节突关节内的神经是游离和包被的,含有P物质和降钙素基因相关肽。治疗方法必须解决这些不同的解剖和生理现象,以提供最高水平的介入治疗。大型、良好的研究已经证明了使用颈小关节内侧支神经阻滞短期缓解症状性疼痛的有效性和安全性。颈椎内侧支射频消融技术可使三分之二的患者持续疼痛缓解长达12个月。最近发表的一项系统综述证实,在射频神经切开术和小关节神经阻滞治疗颈椎小关节疼痛的长期有效性方面,支持使用射频消融的证据为II级。为确保手术成功并减少不良事件的发生,影像学检查是强制性的。透视是一种标准的成像技术,但超声和甚至计算机断层扫描指导已被证明是令人满意的训练有素的介入医师。颈椎小关节及其内侧分支是指导介入治疗的可靠靶点,旨在解决伤害性疼痛,尽管有神经源性成分。未来的研究将反映我们对这些复杂的神经支配解剖网络及其在慢性头痛和颈部疼痛病因学中的作用的不断发展的认识。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Cervical spine pain related to the facet joints

Neck pain is a common diagnostic entity, with a lifetime prevalence of between 65% and 80%. Appreciation of the role of the cervical facet joints in the etiology of cervical spine pain is paramount to providing sustained pain relief for individuals suffering from degenerative and posttraumatic neck pain. Studies have demonstrated that approximately 60% of patients who sustain whiplash-type rear-end motor vehicle collisions would have pain that results from the facet joints alone, or in conjunction with the cervical intervertebral disks. An appreciation of the anatomical foundation for the development of these painful conditions includes knowledge of the dual, overlapping innervation of each cervical facet joint with contributions from levels at, and above the joint. Medial branch nerves invest the joints; are held closely adherent to the articular pillars by tendons of the semispinalis capitis muscles; and can be treated using local anesthetic nerve blocks followed by radiofrequency (RF) procedures for prolonged benefit. Nerves in facet joints contain modified nociceptors, including silent nociceptors, low-threshold mechanoreceptors, and mechanically sensitive nociceptors. Nerves within facet joints are both free and encapsulated and contain Substance P and calcitonin gene–related peptide. Treatment approaches must address these diverse anatomical and physiological phenomena to provide the highest level of interventional therapy. Large, well-conducted studies have demonstrated the efficacy and safety of providing short-term symptomatic pain relief using cervical facet medial branch nerve blocks. Continuous-energy thermal lesioning RF ablation techniques of the cervical medial branches may produce pain relief that persists for up to 12 months in two-thirds of patients so treated. A systematic review of well-conducted studies recently published confirmed that the evidence in favor of using RF ablation is level II for the long-term effectiveness of RF neurotomy and facet joint nerve blocks in managing cervical facet joint pain. Imaging for performing these procedures is mandatory to assure success and to minimize adverse events from occurring. Fluoroscopy is a standard imaging technique, but ultrasound and even computed tomography scan guidance have been documented to be satisfactory in properly trained interventionalists. The cervical facet joints with their medial branches represent a reliable target for directing interventional therapies aimed at addressing nociceptive type pain, albeit with a neurogenic component. Future studies would reflect our evolving appreciation of these intricate anatomical networks of innervation and their role in the etiology of chronic headache and neck pain.

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