{"title":"多种聚乙二醇酸基二嵌段和三嵌段聚酯的单一有机催化剂:合成和表征","authors":"Huan Dong, Zhiheng Feng, Maolin Sun, Shihao Zhu, Jinghong Zhou, Wei Li, Jinxing Ye, Ruihua Cheng","doi":"10.1002/pol.20230231","DOIUrl":null,"url":null,"abstract":"<p>The ring-opening polymerization (ROP) of glycolide (GA), the copolymerization of GA with ε-caprolactone (ε-CL), and the terpolymerization of GA with ε-CL and lactide (LA) were studied over the cheap non-toxic metal-free organocatalyst tetrabutylammonium 2-(carbamyl)benzoate (<b>TBACB</b>). The catalyst with comparable catalytic activity to the comonomers afforded a series of well-defined PGA-based block polymers with ε-CL, LA monomers at high yields by varying feeding methods under bulk and solution conditions. The poly(ɛ-caprolactone-<i>b</i>-glycolic acid)s (PCGAs) and poly(ε-caprolactone-<i>b</i>-lactide-<i>b</i>-glycolide) (PCLGAs) with controllable chain segment composition were obtained by “one-pot” solution copolymerization in mixtures, or semi-batch copolymerization. Due to the high thermal stability of <b>TBACB</b>, the PCGA and PCLGA with high molecular weight (<i>M</i><sub>n</sub> = 6.9 and 10.0 kg mol<sup>−1</sup>) could also be obtained by bulk polymerization at 120 °C by sequential addition of ε-CL, (LA), and GA in a short time (<2.5 h). Compared to the polymers with similar compositions by different methods, the bulk polymerization showed more effective and higher molecular weight. The microstructure characterized by NMR showed highly ordered block polymers with defined chain segments. Two melting transitions (<i>T</i><sub>m</sub>) of PCGA suggested exclusively associated with PCL and PGA segmental chain in the product.</p>","PeriodicalId":199,"journal":{"name":"Journal of Polymer Science Part A: Polymer Chemistry","volume":"61 17","pages":"1971-1983"},"PeriodicalIF":2.7020,"publicationDate":"2023-05-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"A wide range of poly(glycolic acid)-based di- and tri-block polyesters by a single organocatalyst: Synthesis and characterization\",\"authors\":\"Huan Dong, Zhiheng Feng, Maolin Sun, Shihao Zhu, Jinghong Zhou, Wei Li, Jinxing Ye, Ruihua Cheng\",\"doi\":\"10.1002/pol.20230231\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p>The ring-opening polymerization (ROP) of glycolide (GA), the copolymerization of GA with ε-caprolactone (ε-CL), and the terpolymerization of GA with ε-CL and lactide (LA) were studied over the cheap non-toxic metal-free organocatalyst tetrabutylammonium 2-(carbamyl)benzoate (<b>TBACB</b>). The catalyst with comparable catalytic activity to the comonomers afforded a series of well-defined PGA-based block polymers with ε-CL, LA monomers at high yields by varying feeding methods under bulk and solution conditions. The poly(ɛ-caprolactone-<i>b</i>-glycolic acid)s (PCGAs) and poly(ε-caprolactone-<i>b</i>-lactide-<i>b</i>-glycolide) (PCLGAs) with controllable chain segment composition were obtained by “one-pot” solution copolymerization in mixtures, or semi-batch copolymerization. Due to the high thermal stability of <b>TBACB</b>, the PCGA and PCLGA with high molecular weight (<i>M</i><sub>n</sub> = 6.9 and 10.0 kg mol<sup>−1</sup>) could also be obtained by bulk polymerization at 120 °C by sequential addition of ε-CL, (LA), and GA in a short time (<2.5 h). Compared to the polymers with similar compositions by different methods, the bulk polymerization showed more effective and higher molecular weight. 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引用次数: 0
摘要
在廉价无毒无金属有机催化剂四丁基2-氨基甲酰苯甲酸铵(TBACB)上,研究了乙醇酸酯(GA)的开环聚合(ROP)、GA与ε-己内酯(ε-CL)的共聚以及GA与ε-CL和丙交酯(LA)的共聚反应。催化剂的催化活性与单体相当,通过不同的投料方式,在本体条件和溶液条件下,以高收率得到一系列具有良好定义的ε-CL, LA单体的pga基嵌段聚合物。采用“一锅”溶液共聚或半间歇共聚的方法,得到了链段组成可控的聚(ε-己内酯-b-丙交酯-b-乙醇酸)和聚(ε-己内酯-b-丙交酯)。由于TBACB具有较高的热稳定性,在120℃条件下,通过ε-CL、(LA)和GA的连续加成,在较短的时间内(<2.5 h),可以得到高分子量(Mn = 6.9和10.0 kg mol−1)的PCGA和PCLGA。与不同方法制备的相似组分的聚合物相比,本体聚合效果更好,分子量更高。核磁共振表征的微观结构为具有明确链段的高度有序的嵌段聚合物。PCGA的两个熔融转变(Tm)表明与产品中的PCL和PGA段链完全相关。
A wide range of poly(glycolic acid)-based di- and tri-block polyesters by a single organocatalyst: Synthesis and characterization
The ring-opening polymerization (ROP) of glycolide (GA), the copolymerization of GA with ε-caprolactone (ε-CL), and the terpolymerization of GA with ε-CL and lactide (LA) were studied over the cheap non-toxic metal-free organocatalyst tetrabutylammonium 2-(carbamyl)benzoate (TBACB). The catalyst with comparable catalytic activity to the comonomers afforded a series of well-defined PGA-based block polymers with ε-CL, LA monomers at high yields by varying feeding methods under bulk and solution conditions. The poly(ɛ-caprolactone-b-glycolic acid)s (PCGAs) and poly(ε-caprolactone-b-lactide-b-glycolide) (PCLGAs) with controllable chain segment composition were obtained by “one-pot” solution copolymerization in mixtures, or semi-batch copolymerization. Due to the high thermal stability of TBACB, the PCGA and PCLGA with high molecular weight (Mn = 6.9 and 10.0 kg mol−1) could also be obtained by bulk polymerization at 120 °C by sequential addition of ε-CL, (LA), and GA in a short time (<2.5 h). Compared to the polymers with similar compositions by different methods, the bulk polymerization showed more effective and higher molecular weight. The microstructure characterized by NMR showed highly ordered block polymers with defined chain segments. Two melting transitions (Tm) of PCGA suggested exclusively associated with PCL and PGA segmental chain in the product.
期刊介绍:
Part A: Polymer Chemistry is devoted to studies in fundamental organic polymer chemistry and physical organic chemistry. This includes all related topics (such as organic, bioorganic, bioinorganic and biological chemistry of monomers, polymers, oligomers and model compounds, inorganic and organometallic chemistry for catalysts, mechanistic studies, supramolecular chemistry aspects relevant to polymer...