K. de Aguiar Quevedo , C. Jordá Aragón , N. Mancheño Franch , G. Sales Badía , V. Calvo Medina , A. García Zarza , J. Pastor Guillén
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Enfermedad de Castleman: dos variantes, dos pacientes
Introduction
Castleman's disease (CD) is an uncommon lymphoproliferative disorder most frequently localized in the mediastinum and abdomen.
Two cases of CD with mediastinal localization in our service are described. The first case was found in a 33-year old woman with the plasma cell variant of CD associated to Hodgkin's disease and the second case was found in a 32 year old woman with hyalinevascular type CD.
Discussion
CD, of unknown etiology, is clinically distinguished with two forms, multicentric that affects more than one organ and occurs with general symptoms and can be accompanied by other involvements such as lymphoma. The second one is the localized one, which is more frequent and evolves asymptomatically or with compressive symptoms due to mass effect. In these cases presented, the difference in the clinical presentation of this condition in its two variants can be seen.
Conclusions
CD is an uncommon lymphoproliferative disease whose treatment is tumor resection and whose prognosis is good.
期刊介绍：
Revista de Patología Respiratoria is the scientific journal of the Madrilenian Pulmonology and Thoracic Surgery Society (Neumomadrid). It will consider those original articles related to Pulmonology, Thoracic Surgery and all other related sciences for their possible publication. Other types of articles such as reviews, editorials, special articles, scientific letters and letters to the editor are also published in the journal. It is a quarterly Journal that publishes a total of 4 issues, which contain these types of articles to different extents. All publications submitted will always undergo a peer review and a final decision will be made according to comments from the expert reviewers and members of the Editorial Board. The Journal is published both in Spanish and English. Therefore, the submission of manuscripts written in either Spanish or English is welcome.
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