C. Gutiérrez Ortega , F.J. Gómez de Terreros Sánchez , F.J. Gómez de Terreros Caro , L. Callol Sánchez
{"title":"慢性阻塞性肺病男性6分钟步行试验中氧饱和度与肌肉质量和股四头肌收缩力的关系","authors":"C. Gutiérrez Ortega , F.J. Gómez de Terreros Sánchez , F.J. Gómez de Terreros Caro , L. Callol Sánchez","doi":"10.1016/S1576-9895(11)70113-8","DOIUrl":null,"url":null,"abstract":"<div><h3>Hypothesis</h3><p>Among the causes of muscle dysfunction in COPD, mention has been made of decreased oxygen delivery during exercise. Saturation levels during the 6 minutes walking test could be associated to muscle mass and function.</p></div><div><h3>Population, material and methods</h3><p>A group of 75 males patients, 48 (68.6%) males with COPD in different GOLD stages and 28 (74%) with chronic bronchitis (CB) were studied. Tests performed were spirometry, body mass composition analysis, 6 minutes walking test (6MWT), recording of mean hemoglobin saturation and greater or less than 4%, quadriceps voluntary contraction strength test (QMVC). Work performed (Ww) was determined by the Chuang equation and muscle mass by the Janssen Equation.</p></div><div><h3>Results</h3><p>No statistical differences were found in age, body mass index (BMI), free fat mass index (FFMI), muscle mass index (MMI) and QMVC, 6MWT and Ww between the COPD and CB groups. Desaturation<!--> <!-->≥<!--> <!-->4% was more frequent in the COPD group (p<!--> <!--><<!--> <!-->0.01) and was related with a limitation in the distance walked (p<!--> <!-->=<!--> <!-->0.025). The mean SpO<sub>2</sub> after 6MWT of<!--> <!-->≤<!--> <!-->89% differentiates the COPD from the CB population (p<!--> <!-->=<!--> <!-->0.002). We found no relationship between the different levels of SpO<sub>2</sub> after the walk test and muscle mass parameters (MMI, FFMI).</p><p>There was a statistical difference between patients with a mean SpO<sub>2</sub> after the walk test<!--> <!-->≤<!--> <!-->90% and the distance reached (p<!--> <!-->=<!--> <!-->0.04). When the mean SpO<sub>2</sub> was<!--> <!-->≤<!--> <!-->89%, there was a decrease in the WW (p<!--> <!-->=<!--> <!-->0.032). When the mean SpO2 was<!--> <!-->≤<!--> <!-->88% we found a decrease in the QMVC (p<!--> <!-->=<!--> <!-->0.05).</p></div><div><h3>Conclusions</h3><p>After the 6MWT, SpO<sub>2</sub> is more frequent, this having no relationship with the GOLD stage and is only related with the distance reached. Mean SpO<sub>2</sub> after the 6MWT is more sensitive since it is related to performance parameters in the first place, then with muscle strength, and later with quadriceps contraction strength. We found no relationship between the desaturation parameters studied and the muscle mass measurements.</p></div>","PeriodicalId":37742,"journal":{"name":"Revista de Patologia Respiratoria","volume":"14 3","pages":"Pages 70-77"},"PeriodicalIF":0.0000,"publicationDate":"2011-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/S1576-9895(11)70113-8","citationCount":"1","resultStr":"{\"title\":\"Relación de la saturación de O2 en la prueba de los seis minutos marcha con la masa muscular y la fuerza de contracción del cuádriceps en hombres con EPOC\",\"authors\":\"C. Gutiérrez Ortega , F.J. Gómez de Terreros Sánchez , F.J. Gómez de Terreros Caro , L. Callol Sánchez\",\"doi\":\"10.1016/S1576-9895(11)70113-8\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div><h3>Hypothesis</h3><p>Among the causes of muscle dysfunction in COPD, mention has been made of decreased oxygen delivery during exercise. Saturation levels during the 6 minutes walking test could be associated to muscle mass and function.</p></div><div><h3>Population, material and methods</h3><p>A group of 75 males patients, 48 (68.6%) males with COPD in different GOLD stages and 28 (74%) with chronic bronchitis (CB) were studied. Tests performed were spirometry, body mass composition analysis, 6 minutes walking test (6MWT), recording of mean hemoglobin saturation and greater or less than 4%, quadriceps voluntary contraction strength test (QMVC). Work performed (Ww) was determined by the Chuang equation and muscle mass by the Janssen Equation.</p></div><div><h3>Results</h3><p>No statistical differences were found in age, body mass index (BMI), free fat mass index (FFMI), muscle mass index (MMI) and QMVC, 6MWT and Ww between the COPD and CB groups. Desaturation<!--> <!-->≥<!--> <!-->4% was more frequent in the COPD group (p<!--> <!--><<!--> <!-->0.01) and was related with a limitation in the distance walked (p<!--> <!-->=<!--> <!-->0.025). The mean SpO<sub>2</sub> after 6MWT of<!--> <!-->≤<!--> <!-->89% differentiates the COPD from the CB population (p<!--> <!-->=<!--> <!-->0.002). We found no relationship between the different levels of SpO<sub>2</sub> after the walk test and muscle mass parameters (MMI, FFMI).</p><p>There was a statistical difference between patients with a mean SpO<sub>2</sub> after the walk test<!--> <!-->≤<!--> <!-->90% and the distance reached (p<!--> <!-->=<!--> <!-->0.04). When the mean SpO<sub>2</sub> was<!--> <!-->≤<!--> <!-->89%, there was a decrease in the WW (p<!--> <!-->=<!--> <!-->0.032). When the mean SpO2 was<!--> <!-->≤<!--> <!-->88% we found a decrease in the QMVC (p<!--> <!-->=<!--> <!-->0.05).</p></div><div><h3>Conclusions</h3><p>After the 6MWT, SpO<sub>2</sub> is more frequent, this having no relationship with the GOLD stage and is only related with the distance reached. Mean SpO<sub>2</sub> after the 6MWT is more sensitive since it is related to performance parameters in the first place, then with muscle strength, and later with quadriceps contraction strength. We found no relationship between the desaturation parameters studied and the muscle mass measurements.</p></div>\",\"PeriodicalId\":37742,\"journal\":{\"name\":\"Revista de Patologia Respiratoria\",\"volume\":\"14 3\",\"pages\":\"Pages 70-77\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2011-07-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://sci-hub-pdf.com/10.1016/S1576-9895(11)70113-8\",\"citationCount\":\"1\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Revista de Patologia Respiratoria\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://www.sciencedirect.com/science/article/pii/S1576989511701138\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q4\",\"JCRName\":\"Medicine\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Revista de Patologia Respiratoria","FirstCategoryId":"1085","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S1576989511701138","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q4","JCRName":"Medicine","Score":null,"Total":0}
Relación de la saturación de O2 en la prueba de los seis minutos marcha con la masa muscular y la fuerza de contracción del cuádriceps en hombres con EPOC
Hypothesis
Among the causes of muscle dysfunction in COPD, mention has been made of decreased oxygen delivery during exercise. Saturation levels during the 6 minutes walking test could be associated to muscle mass and function.
Population, material and methods
A group of 75 males patients, 48 (68.6%) males with COPD in different GOLD stages and 28 (74%) with chronic bronchitis (CB) were studied. Tests performed were spirometry, body mass composition analysis, 6 minutes walking test (6MWT), recording of mean hemoglobin saturation and greater or less than 4%, quadriceps voluntary contraction strength test (QMVC). Work performed (Ww) was determined by the Chuang equation and muscle mass by the Janssen Equation.
Results
No statistical differences were found in age, body mass index (BMI), free fat mass index (FFMI), muscle mass index (MMI) and QMVC, 6MWT and Ww between the COPD and CB groups. Desaturation ≥ 4% was more frequent in the COPD group (p < 0.01) and was related with a limitation in the distance walked (p = 0.025). The mean SpO2 after 6MWT of ≤ 89% differentiates the COPD from the CB population (p = 0.002). We found no relationship between the different levels of SpO2 after the walk test and muscle mass parameters (MMI, FFMI).
There was a statistical difference between patients with a mean SpO2 after the walk test ≤ 90% and the distance reached (p = 0.04). When the mean SpO2 was ≤ 89%, there was a decrease in the WW (p = 0.032). When the mean SpO2 was ≤ 88% we found a decrease in the QMVC (p = 0.05).
Conclusions
After the 6MWT, SpO2 is more frequent, this having no relationship with the GOLD stage and is only related with the distance reached. Mean SpO2 after the 6MWT is more sensitive since it is related to performance parameters in the first place, then with muscle strength, and later with quadriceps contraction strength. We found no relationship between the desaturation parameters studied and the muscle mass measurements.
期刊介绍：
Revista de Patología Respiratoria is the scientific journal of the Madrilenian Pulmonology and Thoracic Surgery Society (Neumomadrid). It will consider those original articles related to Pulmonology, Thoracic Surgery and all other related sciences for their possible publication. Other types of articles such as reviews, editorials, special articles, scientific letters and letters to the editor are also published in the journal. It is a quarterly Journal that publishes a total of 4 issues, which contain these types of articles to different extents. All publications submitted will always undergo a peer review and a final decision will be made according to comments from the expert reviewers and members of the Editorial Board. The Journal is published both in Spanish and English. Therefore, the submission of manuscripts written in either Spanish or English is welcome.
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