用renu®1和complete®2溶液处理的亲水隐形眼镜上蛋白质沉积的定量分析

Yi Liu MD, Pei Ying Xie MD, PhD
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引用次数: 4

摘要

本研究的目的是研究新的ReNu®MultiPlus™(ReNu®1)和新的COMPLETE®品牌ComfortPLUS™多用途溶液(COMPLETE®2)在亲水隐形眼镜上的蛋白质沉积清洁能力。使用新的从未佩戴过的亲水性隐形眼镜(SUREVUE®3 etafilcon A, 58%)。将隐形眼镜置于人工泪液中体外浸泡;收集人佩戴的晶状体进行体内实验。使用紫外分光光度计进行测量。COMPLETE®对蛋白质沉积物的清洁效果明显优于ReNu®。在体外实验中,COMPLETE®去除的沉积物量是ReNu®的两倍。在一项体内实验中,这种差异更为显著。这两种溶液的不同清洗效果可能是由于它们的pH值、缓冲液或清洗成分的不同。这种差异不是由于浸泡时间,因为每种溶液都达到一个峰值,之后没有额外的蛋白质沉积物被去除。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Quantitative assay of protein deposits on hydrophilic contact lenses treated with renu®1 and complete®2 solutions

The purpose of this study was to investigate the protein deposit cleaning ability of new ReNu® MultiPlus™ (ReNu®1) and new COMPLETE® brand ComfortPLUS™ Multi-Purpose Solution (COMPLETE®2) on hydrophilic contact lenses. New never-worn hydrophilic contact lenses (SUREVUE®3 etafilcon A, 58%) were used. Contact lenses were incubated in artificial tear solution for in vitro soaking; human-worn lenses were collected for in vivo assay. The measurements were performed using a UV spectrophotometer. The cleaning efficacy of COMPLETE® on protein deposits was significantly better than that of ReNu®. In the in vitro experiment, COMPLETE® removed about two times the amount of deposits than ReNu® did. In an in vivo experiment, the difference was even more remarkable. The differing cleaning efficacies of the two solutions may be due to differences in their pH, buffers, or cleaning components. The difference was not due to soaking time, as each solution reached a peak point after which no additional protein deposits were removed.

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