淋巴内积液基底膜振动的模拟

Sinyoung Lee, Takuji Koike
{"title":"淋巴内积液基底膜振动的模拟","authors":"Sinyoung Lee,&nbsp;Takuji Koike","doi":"10.1016/j.piutam.2017.08.043","DOIUrl":null,"url":null,"abstract":"<div><p>Endolymphatic hydrops (EH) causes fluctuating hearing loss especially at low frequencies. In this paper, we analyze EH with the human cochlear finite element model which includes activity of the outer hair cells (OHC). EH was simulated by loading static pressure on the surface of the basilar membrane (BM) of the cochlear model. The vibrations of the BM in the EH model were calculated by applying sound pressure to the stapes, and the results were compared with those in the normal cochlea model. As a result, the distribution of characteristic frequency (CF) was changed and the displacement of the BM was decreased by loading static pressure to the BM. This suggests that the mechanism of hearing loss was caused by EH.</p></div>","PeriodicalId":74499,"journal":{"name":"Procedia IUTAM","volume":null,"pages":null},"PeriodicalIF":0.0000,"publicationDate":"2017-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.piutam.2017.08.043","citationCount":"6","resultStr":"{\"title\":\"Simulation of the Basilar Membrane Vibration of Endolymphatic hydrops\",\"authors\":\"Sinyoung Lee,&nbsp;Takuji Koike\",\"doi\":\"10.1016/j.piutam.2017.08.043\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div><p>Endolymphatic hydrops (EH) causes fluctuating hearing loss especially at low frequencies. In this paper, we analyze EH with the human cochlear finite element model which includes activity of the outer hair cells (OHC). EH was simulated by loading static pressure on the surface of the basilar membrane (BM) of the cochlear model. The vibrations of the BM in the EH model were calculated by applying sound pressure to the stapes, and the results were compared with those in the normal cochlea model. As a result, the distribution of characteristic frequency (CF) was changed and the displacement of the BM was decreased by loading static pressure to the BM. This suggests that the mechanism of hearing loss was caused by EH.</p></div>\",\"PeriodicalId\":74499,\"journal\":{\"name\":\"Procedia IUTAM\",\"volume\":null,\"pages\":null},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2017-01-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://sci-hub-pdf.com/10.1016/j.piutam.2017.08.043\",\"citationCount\":\"6\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Procedia IUTAM\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://www.sciencedirect.com/science/article/pii/S2210983817301554\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Procedia IUTAM","FirstCategoryId":"1085","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S2210983817301554","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 6

摘要

内淋巴水肿(EH)引起波动性听力损失,特别是在低频率。本文采用包含外毛细胞活动的人耳蜗有限元模型对其进行了分析。通过在耳蜗基底膜(BM)表面施加静压来模拟EH。通过对镫骨施加声压的方法计算了EH模型中耳蜗的振动,并与正常耳蜗模型进行了比较。结果表明,施加静压力改变了基板的特征频率分布,减小了基板的位移。提示耳聋的机制可能与脑出血有关。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Simulation of the Basilar Membrane Vibration of Endolymphatic hydrops

Endolymphatic hydrops (EH) causes fluctuating hearing loss especially at low frequencies. In this paper, we analyze EH with the human cochlear finite element model which includes activity of the outer hair cells (OHC). EH was simulated by loading static pressure on the surface of the basilar membrane (BM) of the cochlear model. The vibrations of the BM in the EH model were calculated by applying sound pressure to the stapes, and the results were compared with those in the normal cochlea model. As a result, the distribution of characteristic frequency (CF) was changed and the displacement of the BM was decreased by loading static pressure to the BM. This suggests that the mechanism of hearing loss was caused by EH.

求助全文
通过发布文献求助,成功后即可免费获取论文全文。 去求助
来源期刊
自引率
0.00%
发文量
0
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
确定
请完成安全验证×
copy
已复制链接
快去分享给好友吧!
我知道了
右上角分享
点击右上角分享
0
联系我们:info@booksci.cn Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术官方微信