以酿酒酵母为模式生物的抗衰老化合物研究进展

Q2 Medicine
Gulperi Yalcin, Cheol-Koo Lee
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引用次数: 3

摘要

延长寿命和改善衰老相关表型已成为许多研究的目标。一些现有的延长寿命的方法,包括饮食限制和基因操纵,很难应用于人类,其副作用也很难预测。因此,发现能够模拟抗衰老作用或通过细胞内不同代谢诱导寿命延长的化合物是很重要的。在这里,我们总结了最近的研究,以测试各种类型的化合物和材料,利用芽殖酵母显示潜在的抗衰老作用。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Recent studies on anti-aging compounds with Saccharomyces cerevisiae as a model organism

Extension of lifespan and amelioration of aging-associated phenotypes have been targets of many studies. Some of the established methods of increasing lifespan including dietary restriction and genetic manipulation are difficult to apply to humans, and their side effects are hard to predict. For that reason, it is important to discover compounds that can mimic the anti-aging actions or induce lifespan extension through different metabolisms within the cell. Here we summarize the recent studies to test various types of compounds and materials using budding yeast that show potential anti-aging effects.

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来源期刊
Translational Medicine of Aging
Translational Medicine of Aging Medicine-Geriatrics and Gerontology
CiteScore
5.30
自引率
0.00%
发文量
2
审稿时长
103 days
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