lncrna在衰老相关疾病及三维基因组中的功能

Q2 Medicine

Translational Medicine of Aging Pub Date : 2019-01-01 DOI:10.1016/j.tma.2019.06.001

Wanying Zhang, Tengfei Hu, Xiaoyuan Song

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引用次数: 0

摘要

在过去的几十年里，长链非编码rna (lncRNAs)已经被证明在几乎所有的生物过程中发挥着重要作用。衰老是一个渐进的、不可逆转的生物过程，与许多人类疾病有关。在这篇综述中，我们将讨论lncrna在影响衰老相关疾病进展中的功能和机制。此外，我们将讨论lncrna在三维基因组组织中的作用。

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The function of lncRNAs in aging-related diseases and 3D genome

In the past decades, long noncoding RNAs (lncRNAs) have been indicated to play important roles in almost every biological process. Aging is a gradual and irreversible biological processes and associated with many human diseases. In this review, we will discuss the function and mechanism of lncRNAs in influencing the progression of aging-related diseases. Moreover, we will discuss the roles of lncRNAs in 3D genome organization.

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来源期刊

Translational Medicine of Aging Medicine-Geriatrics and Gerontology

CiteScore

5.30

自引率

0.00%

发文量

审稿时长

103 days