{"title":"双脑经颅直流电刺激对布洛卡失语症言语功能的影响","authors":"Saha Yekta , Alia Saberi , Kamran Ezzati , Kambiz Rohampour , Somayeh Ahmadi Gooraji , Samaneh Ghorbani Shirkouhi , Sasan Andalib","doi":"10.1016/j.jneuroling.2022.101087","DOIUrl":null,"url":null,"abstract":"<div><p><span><span><span>Aphasia is one of the most common deficits occurring after stroke that remains, at least in part, even after speech therapy and medication </span>treatment. Non-invasive </span>direct current transcranial stimulation<span> (tDCS) is used to improve brain function by induction of neural plasticity. This study investigated the effect of bi-hemispheric tDCS on verbal function </span></span>in patients with stroke-induced Broca's aphasia.</p><p>Thirty patients with Broca's aphasia due to ischemic stroke<span>, referred to an academic hospital in Guilan Province, Iran, in 2019-20, were studied. Patients were divided into two groups receiving seven sessions of either active or sham tDCS. The tDCS sessions began 10–20 days after stroke onset. The severity of aphasia before and after the intervention and a 3-month follow-up were assessed by the Persian version of the Western Battery-1 test (P-WAB-1). T-test, ANOVA, and Repeated Measurement were used for data analyses.</span></p><p>The mean P-WAB-1 score was significantly higher in the intervention group both early after tDCS (P ≤ 0.0001) and on the 3-months follow-up (P ≤ 0001). Linear regression analysis indicated that tDCS had a positive effect on verbal performance scores independent of age, sex, and lesion volume (Regression coefficient = −33.3).</p><p>Bi-hemispheric tDCS effectively improves verbal function in Broca's aphasia in the sub-acute phase of ischemic stroke.</p></div>","PeriodicalId":50118,"journal":{"name":"Journal of Neurolinguistics","volume":null,"pages":null},"PeriodicalIF":1.2000,"publicationDate":"2022-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"The effect of bi-hemispheric transcranial direct current stimulation on verbal function in Broca's aphasia\",\"authors\":\"Saha Yekta , Alia Saberi , Kamran Ezzati , Kambiz Rohampour , Somayeh Ahmadi Gooraji , Samaneh Ghorbani Shirkouhi , Sasan Andalib\",\"doi\":\"10.1016/j.jneuroling.2022.101087\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div><p><span><span><span>Aphasia is one of the most common deficits occurring after stroke that remains, at least in part, even after speech therapy and medication </span>treatment. Non-invasive </span>direct current transcranial stimulation<span> (tDCS) is used to improve brain function by induction of neural plasticity. This study investigated the effect of bi-hemispheric tDCS on verbal function </span></span>in patients with stroke-induced Broca's aphasia.</p><p>Thirty patients with Broca's aphasia due to ischemic stroke<span>, referred to an academic hospital in Guilan Province, Iran, in 2019-20, were studied. Patients were divided into two groups receiving seven sessions of either active or sham tDCS. The tDCS sessions began 10–20 days after stroke onset. The severity of aphasia before and after the intervention and a 3-month follow-up were assessed by the Persian version of the Western Battery-1 test (P-WAB-1). T-test, ANOVA, and Repeated Measurement were used for data analyses.</span></p><p>The mean P-WAB-1 score was significantly higher in the intervention group both early after tDCS (P ≤ 0.0001) and on the 3-months follow-up (P ≤ 0001). Linear regression analysis indicated that tDCS had a positive effect on verbal performance scores independent of age, sex, and lesion volume (Regression coefficient = −33.3).</p><p>Bi-hemispheric tDCS effectively improves verbal function in Broca's aphasia in the sub-acute phase of ischemic stroke.</p></div>\",\"PeriodicalId\":50118,\"journal\":{\"name\":\"Journal of Neurolinguistics\",\"volume\":null,\"pages\":null},\"PeriodicalIF\":1.2000,\"publicationDate\":\"2022-08-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Journal of Neurolinguistics\",\"FirstCategoryId\":\"102\",\"ListUrlMain\":\"https://www.sciencedirect.com/science/article/pii/S0911604422000318\",\"RegionNum\":3,\"RegionCategory\":\"心理学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q2\",\"JCRName\":\"LINGUISTICS\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of Neurolinguistics","FirstCategoryId":"102","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S0911604422000318","RegionNum":3,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"LINGUISTICS","Score":null,"Total":0}
The effect of bi-hemispheric transcranial direct current stimulation on verbal function in Broca's aphasia
Aphasia is one of the most common deficits occurring after stroke that remains, at least in part, even after speech therapy and medication treatment. Non-invasive direct current transcranial stimulation (tDCS) is used to improve brain function by induction of neural plasticity. This study investigated the effect of bi-hemispheric tDCS on verbal function in patients with stroke-induced Broca's aphasia.
Thirty patients with Broca's aphasia due to ischemic stroke, referred to an academic hospital in Guilan Province, Iran, in 2019-20, were studied. Patients were divided into two groups receiving seven sessions of either active or sham tDCS. The tDCS sessions began 10–20 days after stroke onset. The severity of aphasia before and after the intervention and a 3-month follow-up were assessed by the Persian version of the Western Battery-1 test (P-WAB-1). T-test, ANOVA, and Repeated Measurement were used for data analyses.
The mean P-WAB-1 score was significantly higher in the intervention group both early after tDCS (P ≤ 0.0001) and on the 3-months follow-up (P ≤ 0001). Linear regression analysis indicated that tDCS had a positive effect on verbal performance scores independent of age, sex, and lesion volume (Regression coefficient = −33.3).
Bi-hemispheric tDCS effectively improves verbal function in Broca's aphasia in the sub-acute phase of ischemic stroke.
期刊介绍：
The Journal of Neurolinguistics is an international forum for the integration of the neurosciences and language sciences. JNL provides for rapid publication of novel, peer-reviewed research into the interaction between language, communication and brain processes. The focus is on rigorous studies of an empirical or theoretical nature and which make an original contribution to our knowledge about the involvement of the nervous system in communication and its breakdowns. Contributions from neurology, communication disorders, linguistics, neuropsychology and cognitive science in general are welcome. Published articles will typically address issues relating some aspect of language or speech function to its neurological substrates with clear theoretical import. Interdisciplinary work on any aspect of the biological foundations of language and its disorders resulting from brain damage is encouraged. Studies of normal subjects, with clear reference to brain functions, are appropriate. Group-studies on well defined samples and case studies with well documented lesion or nervous system dysfunction are acceptable. The journal is open to empirical reports and review articles. Special issues on aspects of the relation between language and the structure and function of the nervous system are also welcome.
求助内容：
应助结果提醒方式：
京公网安备 11010802042870号
