E. Pérez-Reyes , J. Rivera-Sánchez , A.I. Servín-Caamaño , E. Pérez-Torres , J.M. Abdo-Francis , F. Higuera-de la Tijera
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Characteristics of cirrhotic patients with and without malnutrition were compared.</p></div><div><h3>Results</h3><p>103 cirrhotic patients were included, 58 (56.3%) were women; the media of age was 55<!--> <!-->±<!--> <!-->12.2 years. According to SGA, 45 patients (43.7%) were classified as well-nourished, and 58 (56.3%) as malnourished. The development of serious complications was related to nutritional status. 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引用次数: 9
摘要
肝硬化患者有营养不良的危险，这已被认为是发病率和死亡率的预测指标。本研究的目的是比较有营养不良和没有营养不良的肝硬化患者发生严重并发症(静脉曲张出血、腹水、肝性脑病和感染)的频率。研究对象和方法:观察性、分析性、横断面研究。采用主观总体评价法(SGA)评价肝硬化患者的营养状况。比较有无营养不良的肝硬化患者的特点。结果纳入103例肝硬化患者，女性58例(56.3%);年龄中位数为55±12.2岁。根据SGA, 45例(43.7%)患者被分类为营养良好，58例(56.3%)患者被分类为营养不良。严重并发症的发生与营养状况有关。营养不良患者发生腹水的频率更高(67.2% vs. 42.2%， P = 0.01, OR = 2.8;95%置信区间:1.3—-6.3)和感染(21.4%比6.7%,P = 0.03 = 4.5;95% ci: 1.2-16.6)。结论肝硬化营养不良患者腹水、细菌和真菌感染等严重并发症的发生率高于营养良好患者。
Malnutrition is related to a higher frequency of serious complications in patients with cirrhosis
Introduction
Patients with cirrhosis are at risk of malnutrition and this has been recognized as a predictor of morbidity and mortality. The aim of this study was to compare the frequency of serious complications (variceal bleeding, ascites, hepatic encephalopathy and infections) between cirrhotic patients with and without malnutrition.
Subjects and methods
An observational, analytic, cross-sectional study. The nutritional status of cirrhotic patients was evaluated according to Subjective Global Assessment (SGA). Characteristics of cirrhotic patients with and without malnutrition were compared.
Results
103 cirrhotic patients were included, 58 (56.3%) were women; the media of age was 55 ± 12.2 years. According to SGA, 45 patients (43.7%) were classified as well-nourished, and 58 (56.3%) as malnourished. The development of serious complications was related to nutritional status. Malnourished patients had higher frequency of development of ascites (67.2% vs. 42.2%, P = 0.01, OR = 2.8; 95% CI: 1.3–6.3) and infections (21.4% vs. 6.7%, P = 0.03, OR = 4.5; 95% CI: 1.2–16.6).
Conclusions
The presence of serious complications, such as, ascites and development of bacterial and fungal infections, was more frequent between cirrhotic patients with malnutrition than in those well-nourished.
期刊介绍：
The Medical Journal of the Hospital General de Mexico is the official organ of the Medical Society of the Hospital General de Mexico. The journal accepts articles in Spanish or in English on the field of hospital medicine. The journal publishes original articles, clinical cases, reviews articles, history notes, issues on medical education, short communications and editorials at the invitation of the Society. All articles are double blind peer reviewed by at least 2 reviewers and finally classified as accepted or rejected by the Editorial Board.
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