{"title":"14c -乐果在鳞翅目幼虫体内的活化作用","authors":"N.A. Khan","doi":"10.1016/0742-8413(93)90058-S","DOIUrl":null,"url":null,"abstract":"<div><p>1. Dimethoate was generally more toxic when ingested than when applied topically to similar sized larvae of <em>Mamestra brassicae</em> (L) (4th-instar), <em>Spodoptera littoralis</em> (Boisd) (4th-instar), <em>Pieris brassicae</em> (L) (3rd-instar) and <em>Bombyx mori</em> (L) (2nd-instar).</p><p>2. In vivo oxidation of ingested <sup>14</sup>C-dimethoate to omethoate decreased in the order of <em>S. littoralis > P. brassicae > B. mori</em> and followed the order of decreasing susceptibility.</p><p>3. <sup>14</sup>C-dimethoate was regurgitated and excreted and was related to feeding rates of the species.</p><p>4. The implications of the above data in relation to causes of variation in interspecies susceptibility with particular reference to concepts of resistance as influenced by polyphagy versus monophagy are discussed.</p></div>","PeriodicalId":72650,"journal":{"name":"Comparative biochemistry and physiology. C: Comparative pharmacology","volume":"105 1","pages":"Pages 63-68"},"PeriodicalIF":0.0000,"publicationDate":"1993-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/0742-8413(93)90058-S","citationCount":"5","resultStr":"{\"title\":\"Activation of 14C-dimethoate in lepidopterous larvae\",\"authors\":\"N.A. Khan\",\"doi\":\"10.1016/0742-8413(93)90058-S\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div><p>1. Dimethoate was generally more toxic when ingested than when applied topically to similar sized larvae of <em>Mamestra brassicae</em> (L) (4th-instar), <em>Spodoptera littoralis</em> (Boisd) (4th-instar), <em>Pieris brassicae</em> (L) (3rd-instar) and <em>Bombyx mori</em> (L) (2nd-instar).</p><p>2. In vivo oxidation of ingested <sup>14</sup>C-dimethoate to omethoate decreased in the order of <em>S. littoralis > P. brassicae > B. mori</em> and followed the order of decreasing susceptibility.</p><p>3. <sup>14</sup>C-dimethoate was regurgitated and excreted and was related to feeding rates of the species.</p><p>4. The implications of the above data in relation to causes of variation in interspecies susceptibility with particular reference to concepts of resistance as influenced by polyphagy versus monophagy are discussed.</p></div>\",\"PeriodicalId\":72650,\"journal\":{\"name\":\"Comparative biochemistry and physiology. C: Comparative pharmacology\",\"volume\":\"105 1\",\"pages\":\"Pages 63-68\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"1993-05-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://sci-hub-pdf.com/10.1016/0742-8413(93)90058-S\",\"citationCount\":\"5\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Comparative biochemistry and physiology. C: Comparative pharmacology\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://www.sciencedirect.com/science/article/pii/074284139390058S\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Comparative biochemistry and physiology. C: Comparative pharmacology","FirstCategoryId":"1085","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/074284139390058S","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 5
摘要
1. 一般情况下，食入乐果对4龄、4龄、3龄和2龄家蚕幼虫的毒性大于外用乐果。摄入的14c -乐果在体内氧化成乐果的顺序依次递减;芸苔属;敏感性依次递减。14 - c -乐果反刍排泄，与食性有关。本文讨论了上述数据对种间易感性变异原因的影响，特别是对受多食与单食影响的抗性概念的影响。
Activation of 14C-dimethoate in lepidopterous larvae
1. Dimethoate was generally more toxic when ingested than when applied topically to similar sized larvae of Mamestra brassicae (L) (4th-instar), Spodoptera littoralis (Boisd) (4th-instar), Pieris brassicae (L) (3rd-instar) and Bombyx mori (L) (2nd-instar).
2. In vivo oxidation of ingested 14C-dimethoate to omethoate decreased in the order of S. littoralis > P. brassicae > B. mori and followed the order of decreasing susceptibility.
3. 14C-dimethoate was regurgitated and excreted and was related to feeding rates of the species.
4. The implications of the above data in relation to causes of variation in interspecies susceptibility with particular reference to concepts of resistance as influenced by polyphagy versus monophagy are discussed.
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