关于糖尿病患者围手术期管理的新NHS糖尿病指南

K. Dhatariya, A. Kilvert
{"title":"关于糖尿病患者围手术期管理的新NHS糖尿病指南","authors":"K. Dhatariya, A. Kilvert","doi":"10.1002/PDI.1591","DOIUrl":null,"url":null,"abstract":"much of what we do in our profession has been determined by evidence from large, long-term intervention trials. These provide a strong evidence base for recommending person specific targets for HbA1c, blood pressure and lipids. However, as diabetes specialists we also have an important role in ensuring that the condition is well managed during hospital admission and in this area there is very limited evidence on which to base recommendations. The incidence of diabetes is rising exponentially and as a consequence the number of inpatients with diabetes is also rising. Attention is therefore focusing on inpatient care, with recognition that this is frequently suboptimal. The 2010 National Inpatient Audit reports a mean diabetes prevalence of 15% (range 6.6–24.3%) among inpatients in acute hospitals.1 The audit shows that patients with diabetes experience high levels of medication and management errors and increased length of stay.1,2 Guidelines for the management of inpatients with diabetes are needed to standardise and improve care across the UK. Surgery in people with diabetes is a neglected area, with surgeons and anaesthetists often happy with the idea of ‘permissive hyperglycaemia’, assuming that short (or even long) term hyperglycaemia is less likely to do the patient harm than a hypoglycaemic episode while under anaesthetic. However, recent data from the US have demonstrated that people with diabetes undergoing surgery have an almost 50% greater chance of postoperative mortality than those with normal glucose tolerance and have adverse consequences in all measures of postoperative morbidity.3 Furthermore, people with preoperative hyperglycaemia, who were not previously known to have diabetes, had a risk of perioperative death up to 12 times that of people without diabetes, rising to 40 times if the hyperglycaemia persisted postoperatively.3 These are powerful data and if you could tell your surgical colleagues that you could reduce their perioperative mortality by 12-fold without them even putting knife to skin, you would probably get their attention fairly swiftly.","PeriodicalId":92116,"journal":{"name":"Practical diabetes international : the journal for diabetes care teams worldwide","volume":"5 1","pages":"200-201"},"PeriodicalIF":0.0000,"publicationDate":"2011-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1002/PDI.1591","citationCount":"1","resultStr":"{\"title\":\"The new NHS Diabetes guidelines on the perioperative management of people with diabetes\",\"authors\":\"K. Dhatariya, A. Kilvert\",\"doi\":\"10.1002/PDI.1591\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"much of what we do in our profession has been determined by evidence from large, long-term intervention trials. These provide a strong evidence base for recommending person specific targets for HbA1c, blood pressure and lipids. However, as diabetes specialists we also have an important role in ensuring that the condition is well managed during hospital admission and in this area there is very limited evidence on which to base recommendations. The incidence of diabetes is rising exponentially and as a consequence the number of inpatients with diabetes is also rising. Attention is therefore focusing on inpatient care, with recognition that this is frequently suboptimal. The 2010 National Inpatient Audit reports a mean diabetes prevalence of 15% (range 6.6–24.3%) among inpatients in acute hospitals.1 The audit shows that patients with diabetes experience high levels of medication and management errors and increased length of stay.1,2 Guidelines for the management of inpatients with diabetes are needed to standardise and improve care across the UK. Surgery in people with diabetes is a neglected area, with surgeons and anaesthetists often happy with the idea of ‘permissive hyperglycaemia’, assuming that short (or even long) term hyperglycaemia is less likely to do the patient harm than a hypoglycaemic episode while under anaesthetic. However, recent data from the US have demonstrated that people with diabetes undergoing surgery have an almost 50% greater chance of postoperative mortality than those with normal glucose tolerance and have adverse consequences in all measures of postoperative morbidity.3 Furthermore, people with preoperative hyperglycaemia, who were not previously known to have diabetes, had a risk of perioperative death up to 12 times that of people without diabetes, rising to 40 times if the hyperglycaemia persisted postoperatively.3 These are powerful data and if you could tell your surgical colleagues that you could reduce their perioperative mortality by 12-fold without them even putting knife to skin, you would probably get their attention fairly swiftly.\",\"PeriodicalId\":92116,\"journal\":{\"name\":\"Practical diabetes international : the journal for diabetes care teams worldwide\",\"volume\":\"5 1\",\"pages\":\"200-201\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2011-06-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://sci-hub-pdf.com/10.1002/PDI.1591\",\"citationCount\":\"1\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Practical diabetes international : the journal for diabetes care teams worldwide\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.1002/PDI.1591\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Practical diabetes international : the journal for diabetes care teams worldwide","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1002/PDI.1591","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 1

摘要

我们在职业中所做的很多事情都是由大型长期干预试验的证据决定的。这些为推荐HbA1c、血压和血脂的个人特定目标提供了强有力的证据基础。然而,作为糖尿病专家,我们在确保住院期间病情得到良好管理方面也扮演着重要的角色,而在这方面,作为推荐依据的证据非常有限。糖尿病的发病率呈指数级上升,因此住院糖尿病患者的数量也在上升。因此,人们的注意力集中在住院治疗上,并认识到这往往是次优的。2010年全国住院患者审计报告,急性医院住院患者中糖尿病的平均患病率为15%(范围为6.6-24.3%)审计显示,糖尿病患者经历了高水平的用药和管理错误,住院时间延长。1,2需要制定糖尿病住院患者管理指南,以规范和改善整个英国的护理。糖尿病患者的外科手术是一个被忽视的领域,外科医生和麻醉师通常乐于接受“容许性高血糖”的概念,认为短期(甚至长期)高血糖比麻醉时的低血糖发作更不可能对患者造成伤害。然而,最近来自美国的数据表明,接受手术的糖尿病患者术后死亡率比糖耐量正常的患者高出近50%,并且在所有的术后发病率测量中都有不良后果此外,术前患有高血糖的患者,以前不知道是否患有糖尿病,围手术期死亡的风险是无糖尿病患者的12倍,如果术后高血糖持续存在,死亡风险将上升到40倍这些都是有力的数据如果你能告诉你的外科同事你可以将他们的围手术期死亡率降低12倍,甚至不用他们把刀放在皮肤上,你可能会很快引起他们的注意。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
The new NHS Diabetes guidelines on the perioperative management of people with diabetes
much of what we do in our profession has been determined by evidence from large, long-term intervention trials. These provide a strong evidence base for recommending person specific targets for HbA1c, blood pressure and lipids. However, as diabetes specialists we also have an important role in ensuring that the condition is well managed during hospital admission and in this area there is very limited evidence on which to base recommendations. The incidence of diabetes is rising exponentially and as a consequence the number of inpatients with diabetes is also rising. Attention is therefore focusing on inpatient care, with recognition that this is frequently suboptimal. The 2010 National Inpatient Audit reports a mean diabetes prevalence of 15% (range 6.6–24.3%) among inpatients in acute hospitals.1 The audit shows that patients with diabetes experience high levels of medication and management errors and increased length of stay.1,2 Guidelines for the management of inpatients with diabetes are needed to standardise and improve care across the UK. Surgery in people with diabetes is a neglected area, with surgeons and anaesthetists often happy with the idea of ‘permissive hyperglycaemia’, assuming that short (or even long) term hyperglycaemia is less likely to do the patient harm than a hypoglycaemic episode while under anaesthetic. However, recent data from the US have demonstrated that people with diabetes undergoing surgery have an almost 50% greater chance of postoperative mortality than those with normal glucose tolerance and have adverse consequences in all measures of postoperative morbidity.3 Furthermore, people with preoperative hyperglycaemia, who were not previously known to have diabetes, had a risk of perioperative death up to 12 times that of people without diabetes, rising to 40 times if the hyperglycaemia persisted postoperatively.3 These are powerful data and if you could tell your surgical colleagues that you could reduce their perioperative mortality by 12-fold without them even putting knife to skin, you would probably get their attention fairly swiftly.
求助全文
通过发布文献求助,成功后即可免费获取论文全文。 去求助
来源期刊
自引率
0.00%
发文量
0
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
确定
请完成安全验证×
copy
已复制链接
快去分享给好友吧!
我知道了
右上角分享
点击右上角分享
0
联系我们:info@booksci.cn Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术官方微信