{"title":"在身体加速的情况下,具有剪切依赖粘度的血液通过弯曲的狭窄动脉的脉动性流动","authors":"Subrata Mukhopadhyay, Mani Shankar Mandal, Swati Mukhopadhyay","doi":"10.1007/s13367-022-00019-w","DOIUrl":null,"url":null,"abstract":"<div><p>A mathematical model of physiological pulsatile flow of blood through a stenotic flexible artery in the presence of body acceleration is presented in this paper. Streaming blood is considered as a shear-thinning non-Newtonian fluid as proposed by Yeleswarapu (Evaluation of continuum models for characterizing the constitutive behaviour of blood, Ph.D. thesis, Dept. Mech. Eng., University of Pittsburgh, 1996), and a physiological pulsatile flow rate proposed by Pedrizzetti (J Fluid Mech 310:89–111, 1996) has been taken through the tube. Deformation of vessel wall is modelled as a function of flow rate. This computational study of an idealized model may bring some insights for realistic blood flow through a stenotic artery. The novelty of this work lies in the fact that realistic flow of blood through a stenosed artery has been studied as far as possible and a new idea has been provided to describe the arterial wall motion. Governing equations in cylindrical polar coordinates are solved using stream function–vorticity method. Behaviour of various flow quantities is investigated through a parametric study. It is noted that the degree of constriction and body acceleration have important impacts on the haemodynamic parameters such as wall shear stress, oscillatory shear index, and relative residence time. Increasing body acceleration enhances the peak value of wall shear stress, but reduces the oscillatory shear index and relative residence time. Almost 1/4th increase in length of flow separation is found when Froude number raises its value from 0.1 to 0.5, other parametric values remaining fixed. On the other hand, almost 50% increase in the magnitude of the peak value of wall pressure is found when the amplitude of body acceleration takes a value 0.4 (<i>A</i> = 0.4) compared to the without body acceleration case (<i>A</i> = 0). 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It is noted that the degree of constriction and body acceleration have important impacts on the haemodynamic parameters such as wall shear stress, oscillatory shear index, and relative residence time. Increasing body acceleration enhances the peak value of wall shear stress, but reduces the oscillatory shear index and relative residence time. Almost 1/4th increase in length of flow separation is found when Froude number raises its value from 0.1 to 0.5, other parametric values remaining fixed. On the other hand, almost 50% increase in the magnitude of the peak value of wall pressure is found when the amplitude of body acceleration takes a value 0.4 (<i>A</i> = 0.4) compared to the without body acceleration case (<i>A</i> = 0). 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引用次数: 3
摘要
本文提出了在人体加速度作用下,狭窄的柔性动脉内血液的生理脉动流的数学模型。流动的血液被认为是Yeleswarapu提出的剪切变薄的非牛顿流体(评价连续介质模型表征血液的本构行为,博士论文,机械学系)。Eng。Pedrizzetti提出的生理脉动流速(J Fluid Mech 310:89-111, 1996)已通过该管进行测量。血管壁的变形模型是流速的函数。这种理想化模型的计算研究可能为狭窄动脉的实际血流提供一些见解。这项工作的新颖之处在于尽可能地研究了狭窄动脉的真实血流,并为描述动脉壁运动提供了一种新的思路。采用流函数涡度法求解柱极坐标系下的控制方程。通过参数化研究考察了不同流量的特性。收缩程度和体加速度对壁面剪切应力、振荡剪切指数和相对停留时间等血流动力学参数有重要影响。体加速度的增大增大了墙体剪应力峰值,但减小了振荡剪切指数和相对停留时间。当弗劳德数从0.1提高到0.5时,在其他参数值保持不变的情况下,流动分离长度增加了近1/4。另一方面,当体加速度幅值为0.4 (a = 0.4)时,壁面压力峰值的幅度比无体加速度情况(a = 0)增加了近50%。这些结果具有重要的作用。
Pulsatile flow of blood with shear-dependent viscosity through a flexible stenosed artery in the presence of body acceleration
A mathematical model of physiological pulsatile flow of blood through a stenotic flexible artery in the presence of body acceleration is presented in this paper. Streaming blood is considered as a shear-thinning non-Newtonian fluid as proposed by Yeleswarapu (Evaluation of continuum models for characterizing the constitutive behaviour of blood, Ph.D. thesis, Dept. Mech. Eng., University of Pittsburgh, 1996), and a physiological pulsatile flow rate proposed by Pedrizzetti (J Fluid Mech 310:89–111, 1996) has been taken through the tube. Deformation of vessel wall is modelled as a function of flow rate. This computational study of an idealized model may bring some insights for realistic blood flow through a stenotic artery. The novelty of this work lies in the fact that realistic flow of blood through a stenosed artery has been studied as far as possible and a new idea has been provided to describe the arterial wall motion. Governing equations in cylindrical polar coordinates are solved using stream function–vorticity method. Behaviour of various flow quantities is investigated through a parametric study. It is noted that the degree of constriction and body acceleration have important impacts on the haemodynamic parameters such as wall shear stress, oscillatory shear index, and relative residence time. Increasing body acceleration enhances the peak value of wall shear stress, but reduces the oscillatory shear index and relative residence time. Almost 1/4th increase in length of flow separation is found when Froude number raises its value from 0.1 to 0.5, other parametric values remaining fixed. On the other hand, almost 50% increase in the magnitude of the peak value of wall pressure is found when the amplitude of body acceleration takes a value 0.4 (A = 0.4) compared to the without body acceleration case (A = 0). These results have a significant role.
期刊介绍:
The Korea-Australia Rheology Journal is devoted to fundamental and applied research with immediate or potential value in rheology, covering the science of the deformation and flow of materials. Emphases are placed on experimental and numerical advances in the areas of complex fluids. The journal offers insight into characterization and understanding of technologically important materials with a wide range of practical applications.