母婴健康对围产期干细胞库的影响。

IF 4.6 3区医学 Q1 BIOCHEMISTRY & MOLECULAR BIOLOGY

Gene Therapy Pub Date : 2023-10-26 DOI:10.1038/s41434-023-00426-w

Dandan Zhu, Mehri Barabadi, Courtney McDonald, Gina Kusuma, Ishmael Miguel Inocencio, Rebecca Lim

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引用次数: 0

摘要

基于细胞的疗法正在评估其在各种疾病中的治疗潜力。妊娠期组织是细胞治疗的有吸引力的来源。世界各地的大量出生确保了足够的妊娠组织，然而，关于出生趋势、分娩方法和妊娠条件对围产期干细胞库的影响，报道的信息有限。这篇综述描述了妊娠组织及其衍生的围产期干细胞库的现状，讨论了为什么出生趋势和分娩方法的变化会影响妊娠组织库的实践，并进一步探讨了常见的妊娠并发症如何潜在地影响围产期干干细胞库。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

Implications of maternal-fetal health on perinatal stem cell banking

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Implications of maternal-fetal health on perinatal stem cell banking

Cell based therapies are being assessed for their therapeutic potential across a variety of diseases. Gestational tissues are attractive sources for cell therapy. The large number of births worldwide ensures sufficient access to gestational tissues, however, limited information has been reported around the impact of birth trends, delivery methods and pregnancy conditions on perinatal stem cell banking. This review describes the current state of banking of gestational tissues and their derived perinatal stem cells, discusses why the changes in birth trends and delivery methods could affect gestational tissue banking practices, and further explores how common pregnancy complications can potentially influence perinatal stem cell banking.

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来源期刊

Gene Therapy 医学-生化与分子生物学

CiteScore

9.70

自引率

2.00%

发文量

审稿时长

4-8 weeks

期刊介绍： Gene Therapy covers both the research and clinical applications of novel therapeutic techniques based on a genetic component. Over the last few decades, significant advances in technologies ranging from identifying novel genetic targets that cause disease through to clinical studies, which show therapeutic benefit, have elevated this multidisciplinary field to the forefront of modern medicine.