Hassaam S Choudhry, Aman M Patel, Aretha Zhu, Sri Guttikonda, Anam Shaikh, Hadeel S Sadek, Christopher W Seery, Mohammad H Dastjerdi
{"title":"宣布突发公共卫生事件后眼科的跨专业阿片类药物处方模式","authors":"Hassaam S Choudhry, Aman M Patel, Aretha Zhu, Sri Guttikonda, Anam Shaikh, Hadeel S Sadek, Christopher W Seery, Mohammad H Dastjerdi","doi":"10.1089/jop.2023.0078","DOIUrl":null,"url":null,"abstract":"<p><p><b><i>Purpose:</i></b> Previous literature has investigated opioid prescription trends in ophthalmology at large, however, little has been done looking at differences between subspecialties. We evaluate if significant trends exist among subspecialties in opioid prescribing patterns. This study aims to illuminate potential over-usage of opioids in ophthalmology that could compromise patient quality of life. <b><i>Methods:</i></b> Medicare data and \"National Plan and Provider Enumeration System (NPPES) Downloadable File\" were queried for cases of ophthalmologists with nonsuppressed opioid prescription data from 2014 to 2019. Ophthalmologists with no subspecialty code or missing regional, gender, degree, or graduation information were excluded. Chi-squared analysis, analysis of variance, <i>t</i>-tests, and multivariate logistic regression were utilized. <b><i>Results:</i></b> Five thousand one hundred forty-three physician records were included in analysis, 450 of which were by cornea subspecialists. Most cornea cases were male, graduated before 2005, and practiced in the South. All subspecialties had a significantly increased likelihood of making opioid claims and higher prescription rates compared with cornea (<i>P</i> < 0.050) besides glaucoma (<i>P</i> = 0.357). Only oculoplastics had significantly increased likelihood of greater total supply of opioids compared with cornea (odds ratio [OR] = 22.195, 95% confidence interval [CI] = 12.209-40.350, <i>P</i> < 0.001), while pediatrics (OR = 4.036, 95% CI = 1.377-11.831, <i>P</i> = 0.011) and neuro-ophthalmology (OR = 4.158, 95% CI = 1.237-13.975, <i>P</i> = 0.021) in addition to oculoplastics (OR = 64.380, 95% CI = 26.306-157.560, <i>P</i> < 0.001) were predicted to have significantly greater opioid beneficiaries. Males, the South/Midwest, and graduating before 2005, all were generally associated with increased likelihood of greater total opioid claims, supply, beneficiaries, and prescription rate (<i>P</i> < 0.050). <b><i>Conclusion:</i></b> Subspecialty, demographic, chronological, and regional trends exist for opioid prescribing patterns in ophthalmology.</p>","PeriodicalId":16689,"journal":{"name":"Journal of Ocular Pharmacology and Therapeutics","volume":" ","pages":"34-47"},"PeriodicalIF":1.9000,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Interspecialty Opioid Prescribing Patterns in Ophthalmology Following Declaration of a Public Health Emergency.\",\"authors\":\"Hassaam S Choudhry, Aman M Patel, Aretha Zhu, Sri Guttikonda, Anam Shaikh, Hadeel S Sadek, Christopher W Seery, Mohammad H Dastjerdi\",\"doi\":\"10.1089/jop.2023.0078\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><p><b><i>Purpose:</i></b> Previous literature has investigated opioid prescription trends in ophthalmology at large, however, little has been done looking at differences between subspecialties. We evaluate if significant trends exist among subspecialties in opioid prescribing patterns. This study aims to illuminate potential over-usage of opioids in ophthalmology that could compromise patient quality of life. <b><i>Methods:</i></b> Medicare data and \\\"National Plan and Provider Enumeration System (NPPES) Downloadable File\\\" were queried for cases of ophthalmologists with nonsuppressed opioid prescription data from 2014 to 2019. Ophthalmologists with no subspecialty code or missing regional, gender, degree, or graduation information were excluded. Chi-squared analysis, analysis of variance, <i>t</i>-tests, and multivariate logistic regression were utilized. <b><i>Results:</i></b> Five thousand one hundred forty-three physician records were included in analysis, 450 of which were by cornea subspecialists. Most cornea cases were male, graduated before 2005, and practiced in the South. All subspecialties had a significantly increased likelihood of making opioid claims and higher prescription rates compared with cornea (<i>P</i> < 0.050) besides glaucoma (<i>P</i> = 0.357). Only oculoplastics had significantly increased likelihood of greater total supply of opioids compared with cornea (odds ratio [OR] = 22.195, 95% confidence interval [CI] = 12.209-40.350, <i>P</i> < 0.001), while pediatrics (OR = 4.036, 95% CI = 1.377-11.831, <i>P</i> = 0.011) and neuro-ophthalmology (OR = 4.158, 95% CI = 1.237-13.975, <i>P</i> = 0.021) in addition to oculoplastics (OR = 64.380, 95% CI = 26.306-157.560, <i>P</i> < 0.001) were predicted to have significantly greater opioid beneficiaries. Males, the South/Midwest, and graduating before 2005, all were generally associated with increased likelihood of greater total opioid claims, supply, beneficiaries, and prescription rate (<i>P</i> < 0.050). <b><i>Conclusion:</i></b> Subspecialty, demographic, chronological, and regional trends exist for opioid prescribing patterns in ophthalmology.</p>\",\"PeriodicalId\":16689,\"journal\":{\"name\":\"Journal of Ocular Pharmacology and Therapeutics\",\"volume\":\" \",\"pages\":\"34-47\"},\"PeriodicalIF\":1.9000,\"publicationDate\":\"2024-01-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Journal of Ocular Pharmacology and Therapeutics\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://doi.org/10.1089/jop.2023.0078\",\"RegionNum\":4,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"2023/10/25 0:00:00\",\"PubModel\":\"Epub\",\"JCR\":\"Q2\",\"JCRName\":\"OPHTHALMOLOGY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of Ocular Pharmacology and Therapeutics","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1089/jop.2023.0078","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2023/10/25 0:00:00","PubModel":"Epub","JCR":"Q2","JCRName":"OPHTHALMOLOGY","Score":null,"Total":0}
引用次数: 0
摘要
目的:先前的文献已经调查了眼科中阿片类药物的处方趋势,但很少研究亚专业之间的差异。我们评估了阿片类药物处方模式在各亚专业之间是否存在显著趋势。这项研究旨在阐明眼科过度使用阿片类药物可能会影响患者的生活质量。方法:查询2014年至2019年眼科医生使用非抑制阿片类药物处方数据的病例的医疗保险数据和“国家计划和提供者计数系统(NPPES)可下载文件”。没有子专业代码或缺少地区、性别、学位或毕业信息的眼科医生被排除在外。采用卡方分析、方差分析、t检验和多变量逻辑回归。结果:分析中包括五千一百四十三份病历,其中450份是角膜专科医生的病历。大多数角膜病例是男性,2005年之前毕业,在南方执业。与角膜相比,所有亚专业提出阿片类药物索赔的可能性都显著增加,处方率也更高(P P = 0.357)。与角膜相比,只有眼肿瘤药物显著增加了阿片类药物总供应量增加的可能性(比值比[OR] = 22.195,95%置信区间[CI] = 12.209-40.350,第页 P = 0.011)和神经眼科(OR = 4.158,95%CI = 1.237-13.975,P = 0.021) = 64.380,95%CI = 26.306-157.560,第页 P 结论:眼科阿片类药物处方模式存在亚专业、人口统计学、时间和区域趋势。
Interspecialty Opioid Prescribing Patterns in Ophthalmology Following Declaration of a Public Health Emergency.
Purpose: Previous literature has investigated opioid prescription trends in ophthalmology at large, however, little has been done looking at differences between subspecialties. We evaluate if significant trends exist among subspecialties in opioid prescribing patterns. This study aims to illuminate potential over-usage of opioids in ophthalmology that could compromise patient quality of life. Methods: Medicare data and "National Plan and Provider Enumeration System (NPPES) Downloadable File" were queried for cases of ophthalmologists with nonsuppressed opioid prescription data from 2014 to 2019. Ophthalmologists with no subspecialty code or missing regional, gender, degree, or graduation information were excluded. Chi-squared analysis, analysis of variance, t-tests, and multivariate logistic regression were utilized. Results: Five thousand one hundred forty-three physician records were included in analysis, 450 of which were by cornea subspecialists. Most cornea cases were male, graduated before 2005, and practiced in the South. All subspecialties had a significantly increased likelihood of making opioid claims and higher prescription rates compared with cornea (P < 0.050) besides glaucoma (P = 0.357). Only oculoplastics had significantly increased likelihood of greater total supply of opioids compared with cornea (odds ratio [OR] = 22.195, 95% confidence interval [CI] = 12.209-40.350, P < 0.001), while pediatrics (OR = 4.036, 95% CI = 1.377-11.831, P = 0.011) and neuro-ophthalmology (OR = 4.158, 95% CI = 1.237-13.975, P = 0.021) in addition to oculoplastics (OR = 64.380, 95% CI = 26.306-157.560, P < 0.001) were predicted to have significantly greater opioid beneficiaries. Males, the South/Midwest, and graduating before 2005, all were generally associated with increased likelihood of greater total opioid claims, supply, beneficiaries, and prescription rate (P < 0.050). Conclusion: Subspecialty, demographic, chronological, and regional trends exist for opioid prescribing patterns in ophthalmology.
期刊介绍:
Journal of Ocular Pharmacology and Therapeutics is the only peer-reviewed journal that combines the fields of ophthalmology and pharmacology to enable optimal treatment and prevention of ocular diseases and disorders. The Journal delivers the latest discoveries in the pharmacokinetics and pharmacodynamics of therapeutics for the treatment of ophthalmic disorders.
Journal of Ocular Pharmacology and Therapeutics coverage includes:
Glaucoma
Cataracts
Retinal degeneration
Ocular infection, trauma, and toxicology
Ocular drug delivery and biotransformation
Ocular pharmacotherapy/clinical trials
Ocular inflammatory and immune disorders
Gene and cell-based therapies
Ocular metabolic disorders
Ocular ischemia and blood flow
Proliferative disorders of the eye
Eyes on Drug Discovery - written by Gary D. Novack, PhD, featuring the latest updates on drug and device pipeline developments as well as policy/regulatory changes by the FDA.