动静脉瘘与移植物策略在老年人导管血液透析中比较效果的临床试验的原因。

IF 1.1 4区 医学 Q3 UROLOGY & NEPHROLOGY
Mariana Murea, Michael Allon
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引用次数: 0

摘要

临床医生和患者在观察性研究的指导下,对晚期肾病患者做出最重要的决定之一:选择“正确”的血液透析血管通路。十多年前,有人呼吁进行随机临床试验,以公平地比较动静脉瘘(AVF)和动静脉移植物(AVG)的临床结果。越来越多的证据表明,AVF和AVGreted结果之间的权衡取决于上下文。在这篇文章中,我们总结了四个证据流,这些证据共同支撑了在使用中心静脉导管进行血液透析的患有合并症的老年人中,两种类型的AV通路之间的平衡负担。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
The reasons for comparative effectiveness clinical trials of arteriovenous fistula versus graft strategy in older adults on hemodialysis with a catheter.

Clinicians and patients are guided by observational studies to make one of the most consequential decisions for patients with advanced kidney disease: the selection of the "right" hemodialysis vascular access. More than a decade ago, a call for randomized clinical trials was made to equitably compare clinical outcomes between arteriovenous (AV) fistulas (AVFs) and AV grafts (AVGs). Mounting evidence suggests that trade-offs between AVF- and AVGrelated outcomes are context dependent. In this article, we summarize four streams of evidence that collectively underpin the burden of equipoise between the two types of AV access in older adults with comorbidities who are on hemodialysis with a central venous catheter.

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来源期刊
Clinical nephrology
Clinical nephrology 医学-泌尿学与肾脏学
CiteScore
2.10
自引率
9.10%
发文量
138
审稿时长
4-8 weeks
期刊介绍: Clinical Nephrology appears monthly and publishes manuscripts containing original material with emphasis on the following topics: prophylaxis, pathophysiology, immunology, diagnosis, therapy, experimental approaches and dialysis and transplantation.
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