难以发现和棘手的治疗:一例系列获得性无核细胞血小板减少症

Human Pathology Reports Pub Date : 2023-09-01 DOI:10.1016/j.hpr.2023.300713

Amina Anwar , Zena Chahine , Dava Piecoro , Melissa Kesler , Ayman Qasrawi

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引用次数: 0

摘要

获得性单核细胞性血小板减少症(AAMT)是一种罕见的血液学疾病，其特征是长期严重的血小板减少，在其他正常的骨髓活检中巨核细胞减少。我们报告了三例，其中两例最终对伊曲波巴治疗有反应，另一例尽管接受了多种药物治疗，但仍死于疾病。这些病例强调了诊断和治疗这种罕见疾病的困难。

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Hard to find and tricky to treat: A case series of acquired amegakaryocytic thrombocytopenia

Acquired amegakaryocytic thrombocytopenia (AAMT) is a rare hematological disorder characterized by prolonged, severe thrombocytopenia, and reduced megakaryocytes on otherwise normal bone marrow biopsy. We report three cases of which two ultimately responded to treatment with eltrombopag, and one who one succumbed to illness despite treatment with multiple agents. These cases emphasize the difficulty of diagnosis and treatment of this rare condition.

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来源期刊

Human Pathology Reports

CiteScore

0.60

自引率

0.00%

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