无症状的人对流行病的动态有多大影响?

Q1 Mathematics
Md Biplob Hossain , Masud M.A. , Arun Kumar Sikder , Md Hamidul Islam
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引用次数: 0

摘要

无症状携带者是传染病的潜在传播源。出现症状的接触者只接受检测,并在需要时在家中或有时在医院隔离。相比之下,无症状个体未经测试,在其整个感染生涯中自由漫步,默默地传播疾病。这项工作旨在探索无症状携带者在流行病传播中的作用,并研究合适的最佳控制策略。我们提出了一个SEIAQR分区模型,将总人口细分为六个不同的分区。为了说明该模型的含义,我们使用2021年6月9日至7月18日期间孟加拉国的新冠肺炎数据估计了无症状个体的数量。然后,我们分析该模型,以探索如果对无症状个体进行随机检测和隔离,疫情是否会消退。最后,为了更好地了解这种未知传播途径的潜力,我们提出了一个最优控制模型,考虑了两种不同的控制策略:个人防护措施和通过随机检测隔离无症状携带者。我们的研究结果表明,同时实施这两种控制策略可以尽早减少疫情。最重要的是,持续努力识别和隔离渐进个体可以放松个人保护措施。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
How big of an impact do asymptomatic people have on the dynamics of an epidemic?

Asymptomatic carriers serve as a potential source of transmission of epidemic diseases. Exposed people who develop symptoms only get tested and remain isolated in their homes or sometimes in hospitals when needed. In contrast, the asymptomatic individuals go untested and spread the disease silently as they roam freely throughout their entire infectious lifetime. The work intends to explore the role of asymptomatic carriers in the transmission of epidemic diseases and investigate suitable optimal control strategies. We propose a SEIAQR compartmental model subdividing the total population into six different compartments. To illustrate the model’s implication, we estimate the number of asymptomatic individuals using COVID-19 data during June 9–July 18, 2021 from Bangladesh. We then analyze the model to explore whether the epidemic subsides if the asymptomatic individuals are tested randomly and isolated. Finally, to gain a better understanding of the potential of this unidentified transmission route, we propose an optimal control model considering two different control strategies: personal protective measures and isolation of asymptomatic carriers through random testing. Our results show that simultaneous implementation of both control strategies can reduce the epidemic early. Most importantly, sustained effort in identifying and isolation of asymptotic individuals allows relaxation in personal protective measures.

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来源期刊
Chaos, Solitons and Fractals: X
Chaos, Solitons and Fractals: X Mathematics-Mathematics (all)
CiteScore
5.00
自引率
0.00%
发文量
15
审稿时长
20 weeks
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