基于证据的上半规管开裂综合征诊断工具

IF 1.4 Q2 OTORHINOLARYNGOLOGY

Journal of Otology Pub Date : 2023-10-01 DOI:10.1016/j.joto.2023.09.006

Christian G. Fritz , Garrett G. Casale , Lulia A. Kana , Robert S. Hong

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引用次数: 0

摘要

目的构建一种基于症状的预测工具，在高分辨率CT上评估上管破裂（SSCD）的可能性。材料和方法在三级神经科转诊中心采用数学模型预测SSCD的放射学证据。结果共纳入168例患者，其中118例经影像学证实为SSCD。在单变量分析中，SSCD存在的重要预测因素是：声音/压力诱导的眩晕（p=0.006）、不平衡（p=0.008）、心律不齐（p=0.008）和自鸣（p=0.034）。多变量分析使14点症状加权工具得以开发，其中得分≥6会引起对SSCD的怀疑（存在的可能性≥70%），R2=0.853结论CT扫描中SSCD的可能性可以根据表现时记录的症状高度确定。使用本文验证的基于证据的诊断工具，任何症状组合的得分≥6都有理由要求进行CT扫描。

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An evidenced-based diagnostic tool for superior semicircular canal dehiscence syndrome

Purpose

To construct a symptoms-based prediction tool to assess the likelihood of superior canal dehiscence (SSCD) on high-resolution CT.

Materials and methods

Mathematical modeling was employed to predict radiologic evidence of SSCD at a tertiary neurotology referral center.

Results

A total of 168 patients were included, of which 118 had imaging-confirmed SSCD. On univariate analysis significant predictors of SSCD presence were: sound/pressure-induced vertigo (p = 0.006), disequilibrium (p = 0.008), hyperacusis (p = 0.008), and autophony (p = 0.034). Multivariate analysis enabled a 14-point symptom-weighted tool to be developed, wherein a score of ≥6 raised the suspicion of SSCD (≥70% likelihood of being present), R² = 0.853.

Conclusions

The likelihood of SSCD on CT scan can be determined with a high degree of certainty based on symptoms recorded at presentation. Using the evidenced-based diagnostic tool validated herein, a score ≥6 with any symptom combination justifies ordering a CT scan.

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来源期刊

Journal of Otology Medicine-Otorhinolaryngology

CiteScore

2.70

自引率

0.00%

发文量

461

审稿时长

18 days

期刊介绍： Journal of Otology is an open access, peer-reviewed journal that publishes research findings from disciplines related to both clinical and basic science aspects of auditory and vestibular system and diseases of the ear. This journal welcomes submissions describing original experimental research that may improve our understanding of the mechanisms underlying problems of basic or clinical significance and treatment of patients with disorders of the auditory and vestibular systems. In addition to original papers the journal also offers invited review articles on current topics written by leading experts in the field. The journal is of primary importance for all scientists and practitioners interested in audiology, otology and neurotology, auditory neurosciences and related disciplines. Journal of Otology welcomes contributions from scholars in all countries and regions across the world.