可降解镁合金在一定时间内提供绝对保护的新设计

IF 5.6 4区 医学 Q1 ENGINEERING, BIOMEDICAL
Irbm Pub Date : 2023-10-01 DOI:10.1016/j.irbm.2023.100784
Jian-Hua Zhu , Xinzhe Gao , Biying Shi , Jiawei Zou , Yu Ru Li , Ke Zeng , Qi Jia , Heng Bo Jiang
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引用次数: 0

摘要

目的镁和镁合金材料作为可生物降解的骨板植入物具有良好的潜力。然而,镁合金的化学活性高、耐腐蚀性差,限制了其实际应用。在这里,我们选择了微氟化(MAF)处理,以提高耐腐蚀性,同时提高镁合金的性能。本研究的目的是确定定点腐蚀对镁合金耐腐蚀性和机械性能的影响,并设计一种新的面向腐蚀的模型,该模型可以在一段时间内提供绝对保护。材料与方法采用MAF处理对镁合金进行表面改性,以提高镁合金的耐蚀性。为了研究涂层和压痕对镁合金耐腐蚀性能的影响,进行了电化学腐蚀实验。值得一提的是,在本实验中,我们测量并分析了样品的力学性能,特别是拉伸强度。结果在创新的压痕试样试验中,由于定点腐蚀的发生,涂层试样的抗拉强度较低。为了避免定点腐蚀造成的机械性能损失,我们提出了一个新的想法(面向腐蚀的设计)。最终,浸渍实验和机械性能分析得出结论,腐蚀导向设计样品可以在没有可检测损失的情况下长期保持机械性能。结论腐蚀导向设计模型可以避免定点腐蚀的干扰,控制腐蚀的集中导向。这为镁合金的临床应用提供了一个新的方向,它可以在创伤治疗中提供完全稳定的骨愈合条件,并避免以前不受控制的腐蚀所造成的缺点。
本文章由计算机程序翻译,如有差异,请以英文原文为准。

New Design to Provide Absolute Protection Within a Certain Period for Biodegradable Magnesium Alloys

New Design to Provide Absolute Protection Within a Certain Period for Biodegradable Magnesium Alloys

Objectives

Magnesium and magnesium alloy materials have excellent potential as biodegradable bone plate implants. However, the practical application of magnesium alloys is limited by their high chemical activity and poor corrosion resistance. Here, we chose a microarc fluorination (MAF) treatment to improve corrosion resistance while enhancing aspects of magnesium alloy properties. The aim of this study was to identify the effect of fixed-point corrosion on the corrosion resistance as well as the mechanical properties of magnesium alloys and to design a new corrosion-oriented model that can provide absolute protection over a period of time.

Material and Methods

MAF treatment is used for surface modification of magnesium alloys to improve the corrosion resistance of magnesium alloys. To investigate the effect of the coating and indentation on the corrosion resistance of Mg alloy, electrochemical corrosion experiments were carried out. It is worth mentioning that in this experiment we measured and analyzed the mechanical properties of the samples, especially the tensile strength.

Results

In the innovative indentation sample test, the coated specimens showed lower tensile strength due to the occurrence of fixed-point corrosion. To avoid the loss of mechanical properties due to fixed-point corrosion, we proposed a new idea (Corrosion-oriented Design). Ultimately, the immersion experiments as well as the mechanical properties analysis concluded that the Corrosion-oriented Design samples could maintain the mechanical properties without detectable loss for a long time.

Conclusion

The Corrosion-oriented Design model can avoid the nuisance of fixed-point corrosion and control the centralized orientation of corrosion. This provides a new direction for the clinical application of magnesium alloys, which may offer a completely stable bone-healing condition in trauma treatment and avoid the drawbacks caused by the previous uncontrolled corrosion.

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来源期刊
Irbm
Irbm ENGINEERING, BIOMEDICAL-
CiteScore
10.30
自引率
4.20%
发文量
81
审稿时长
57 days
期刊介绍: IRBM is the journal of the AGBM (Alliance for engineering in Biology an Medicine / Alliance pour le génie biologique et médical) and the SFGBM (BioMedical Engineering French Society / Société française de génie biologique médical) and the AFIB (French Association of Biomedical Engineers / Association française des ingénieurs biomédicaux). As a vehicle of information and knowledge in the field of biomedical technologies, IRBM is devoted to fundamental as well as clinical research. Biomedical engineering and use of new technologies are the cornerstones of IRBM, providing authors and users with the latest information. Its six issues per year propose reviews (state-of-the-art and current knowledge), original articles directed at fundamental research and articles focusing on biomedical engineering. All articles are submitted to peer reviewers acting as guarantors for IRBM''s scientific and medical content. The field covered by IRBM includes all the discipline of Biomedical engineering. Thereby, the type of papers published include those that cover the technological and methodological development in: -Physiological and Biological Signal processing (EEG, MEG, ECG…)- Medical Image processing- Biomechanics- Biomaterials- Medical Physics- Biophysics- Physiological and Biological Sensors- Information technologies in healthcare- Disability research- Computational physiology- …
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