K. Abdesselam , C. Hannachi , R. Shahbaz , F. Deshours , G. Alquie , H. Kokabi , A. Omer , J.-M. Davaine
{"title":"非侵入性蜂蜜细胞CSRR葡萄糖传感器:设计考虑和建模","authors":"K. Abdesselam , C. Hannachi , R. Shahbaz , F. Deshours , G. Alquie , H. Kokabi , A. Omer , J.-M. Davaine","doi":"10.1016/j.irbm.2022.04.002","DOIUrl":null,"url":null,"abstract":"<div><h3>Objective</h3><p>Over the years, microwave techniques have demonstrated their ability to characterise biological tissues. This study aimed to employ this approach to investigate the changes in the finger's glucose levels and to develop a sensitive sensor that people with diabetes can use.</p></div><div><h3>Materials and methods</h3><p>A simplified four-layer tissue model of the human fingertip was developed to validate the sensor's ability to detect variations in glucose levels. 3D electromagnetic simulations of the sensor with human fingertips inserted in the sensing region while varying the pressure were performed and compared to obtained experimental results using a VNA (vector network analyser).</p></div><div><h3>Results</h3><p>When varying the finger layers thicknesses independently, it was observed that the change in the skin layer thickness influences the frequency the most. It was also noticed that the higher the finger pressure, the more the resonance shifted towards low frequencies with a decreasing magnitude.</p></div><div><h3>Conclusion</h3><p>The achieved results show the impact of the finger's pressure on the sensor. Further investigations are in progress to obtain a good reproducibility of experimental results using a best-fitted pressure protocol on diabetic subjects.</p></div>","PeriodicalId":14605,"journal":{"name":"Irbm","volume":null,"pages":null},"PeriodicalIF":5.6000,"publicationDate":"2023-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"4","resultStr":"{\"title\":\"A Non-Invasive Honey-Cell CSRR Glucose Sensor: Design Considerations and Modelling\",\"authors\":\"K. Abdesselam , C. Hannachi , R. Shahbaz , F. Deshours , G. Alquie , H. Kokabi , A. Omer , J.-M. Davaine\",\"doi\":\"10.1016/j.irbm.2022.04.002\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div><h3>Objective</h3><p>Over the years, microwave techniques have demonstrated their ability to characterise biological tissues. This study aimed to employ this approach to investigate the changes in the finger's glucose levels and to develop a sensitive sensor that people with diabetes can use.</p></div><div><h3>Materials and methods</h3><p>A simplified four-layer tissue model of the human fingertip was developed to validate the sensor's ability to detect variations in glucose levels. 3D electromagnetic simulations of the sensor with human fingertips inserted in the sensing region while varying the pressure were performed and compared to obtained experimental results using a VNA (vector network analyser).</p></div><div><h3>Results</h3><p>When varying the finger layers thicknesses independently, it was observed that the change in the skin layer thickness influences the frequency the most. It was also noticed that the higher the finger pressure, the more the resonance shifted towards low frequencies with a decreasing magnitude.</p></div><div><h3>Conclusion</h3><p>The achieved results show the impact of the finger's pressure on the sensor. Further investigations are in progress to obtain a good reproducibility of experimental results using a best-fitted pressure protocol on diabetic subjects.</p></div>\",\"PeriodicalId\":14605,\"journal\":{\"name\":\"Irbm\",\"volume\":null,\"pages\":null},\"PeriodicalIF\":5.6000,\"publicationDate\":\"2023-02-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"4\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Irbm\",\"FirstCategoryId\":\"5\",\"ListUrlMain\":\"https://www.sciencedirect.com/science/article/pii/S1959031822000343\",\"RegionNum\":4,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q1\",\"JCRName\":\"ENGINEERING, BIOMEDICAL\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Irbm","FirstCategoryId":"5","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S1959031822000343","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"ENGINEERING, BIOMEDICAL","Score":null,"Total":0}
A Non-Invasive Honey-Cell CSRR Glucose Sensor: Design Considerations and Modelling
Objective
Over the years, microwave techniques have demonstrated their ability to characterise biological tissues. This study aimed to employ this approach to investigate the changes in the finger's glucose levels and to develop a sensitive sensor that people with diabetes can use.
Materials and methods
A simplified four-layer tissue model of the human fingertip was developed to validate the sensor's ability to detect variations in glucose levels. 3D electromagnetic simulations of the sensor with human fingertips inserted in the sensing region while varying the pressure were performed and compared to obtained experimental results using a VNA (vector network analyser).
Results
When varying the finger layers thicknesses independently, it was observed that the change in the skin layer thickness influences the frequency the most. It was also noticed that the higher the finger pressure, the more the resonance shifted towards low frequencies with a decreasing magnitude.
Conclusion
The achieved results show the impact of the finger's pressure on the sensor. Further investigations are in progress to obtain a good reproducibility of experimental results using a best-fitted pressure protocol on diabetic subjects.
期刊介绍:
IRBM is the journal of the AGBM (Alliance for engineering in Biology an Medicine / Alliance pour le génie biologique et médical) and the SFGBM (BioMedical Engineering French Society / Société française de génie biologique médical) and the AFIB (French Association of Biomedical Engineers / Association française des ingénieurs biomédicaux).
As a vehicle of information and knowledge in the field of biomedical technologies, IRBM is devoted to fundamental as well as clinical research. Biomedical engineering and use of new technologies are the cornerstones of IRBM, providing authors and users with the latest information. Its six issues per year propose reviews (state-of-the-art and current knowledge), original articles directed at fundamental research and articles focusing on biomedical engineering. All articles are submitted to peer reviewers acting as guarantors for IRBM''s scientific and medical content. The field covered by IRBM includes all the discipline of Biomedical engineering. Thereby, the type of papers published include those that cover the technological and methodological development in:
-Physiological and Biological Signal processing (EEG, MEG, ECG…)-
Medical Image processing-
Biomechanics-
Biomaterials-
Medical Physics-
Biophysics-
Physiological and Biological Sensors-
Information technologies in healthcare-
Disability research-
Computational physiology-
…