地塞米松和布比卡因联合加导管封堵器对全膝关节置换术患者关节周围浸润的疗效:一项回顾性病例匹配研究。

IF 16.4 1区 化学 Q1 CHEMISTRY, MULTIDISCIPLINARY
Accounts of Chemical Research Pub Date : 2023-10-12 eCollection Date: 2023-01-01 DOI:10.1155/2023/7356192
Varah Yuenyongviwat, Bunyaporn Wuttiworawanit, Nipat Panichnantho, Theerawit Hongnaparak, Khanin Iamthanaporn
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引用次数: 0

摘要

目的:关节周围浸润(PI)是全膝关节置换术(TKA)中用于术后疼痛管理的常见程序。这项回顾性病例匹配研究旨在评估地塞米松和布比卡因联合内收肌管阻滞(ACB)的PI的有效性,并将其与单独使用ACB在减轻TKA患者术后疼痛方面的效果进行比较。方法:收集66名由单一外科医生行TKA的患者的数据。其中33人接受了ACB + PI和33单独接受ACB。然而,两组患者均采用了相同的手术技术和术后护理方案。比较两组患者的疼痛评分和芬太尼用量。结果:ACB + PI组的疼痛评分在8、16、24和48分明显低于单独ACB组 术后小时(p分别为0.033、0.004、0.038和0.049)。单用ACB组需要芬太尼作为抢救药物的患者比例(90.9%)明显高于ACB组 + PI组(69.7%,p=0.03)。ACB的芬太尼总消耗量也较低 + 结论:地塞米松和布比卡因联合ACB关节周围注射在减少TKA患者术后疼痛和芬太尼消耗方面比单独ACB更有效。比较不同剂量地塞米松或其他鸡尾酒方案的进一步研究可能会为这种方法提供更多的见解。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Efficacy of Periarticular Infiltration with Dexamethasone and Bupivacaine plus Adductor Canal Block Relative to That of Adductor Canal Block Alone for Patients Undergoing Total Knee Arthroplasty: A Retrospective Case-Matched Study.

Purpose: Periarticular infiltration (PI) is a common procedure during total knee arthroplasty (TKA) for postoperative pain management. This retrospective, case-matched study aimed to evaluate the effectiveness of PI with dexamethasone and bupivacaine in combination with an adductor canal block (ACB) and compare it with that of ACB alone in reducing postoperative pain in patients with TKA.

Methods: Data were collected from 66 patients who underwent TKA performed by a single surgeon. Thirty-three of them received ACB + PI, and 33 received ACB alone. However, both groups underwent identical surgical techniques and postoperative care protocols. The pain scores and fentanyl consumption of the two groups were compared.

Results: The ACB + PI group had significantly lower pain scores than the ACB alone group at 8, 16, 24, and 48 hours postoperatively (p=0.033, 0.004, 0.038, and 0.049, respectively). The percentage of patients requiring fentanyl as a rescue medication was significantly higher for the ACB alone group (90.9%) than for the ACB + PI group (69.7%, p=0.03). The total fentanyl consumption was also lower for the ACB + PI group (p < 0.001).

Conclusion: The periarticular injection of the combination of dexamethasone and bupivacaine plus ACB was more effective than ACB alone in reducing postoperative pain and fentanyl consumption in patients undergoing TKA. Further studies comparing different doses of dexamethasone or other cocktail regimens may provide additional insights into this approach.

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来源期刊
Accounts of Chemical Research
Accounts of Chemical Research 化学-化学综合
CiteScore
31.40
自引率
1.10%
发文量
312
审稿时长
2 months
期刊介绍: Accounts of Chemical Research presents short, concise and critical articles offering easy-to-read overviews of basic research and applications in all areas of chemistry and biochemistry. These short reviews focus on research from the author’s own laboratory and are designed to teach the reader about a research project. In addition, Accounts of Chemical Research publishes commentaries that give an informed opinion on a current research problem. Special Issues online are devoted to a single topic of unusual activity and significance. Accounts of Chemical Research replaces the traditional article abstract with an article "Conspectus." These entries synopsize the research affording the reader a closer look at the content and significance of an article. Through this provision of a more detailed description of the article contents, the Conspectus enhances the article's discoverability by search engines and the exposure for the research.
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