Patrícia Glombowsky, Gabriela Campigotto, Maiara Sulzbach-Marchiori, Jorge A. Favaretto, Gabriela Miotto-Galli, A. S. Da silva
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Use of secnidazole and homeopathy for giardiasis control in dogs
Dogs with Giardia infections have diarrhea that persists for days, even after treatment. We managed canine giardiasis using two distinct approaches: treatment with the antiprotozoan secnidazole alone; and secnidazole plus a homeopathic product that is indicated for control of diarrhea in dogs. Treatment I: Ten beagle dogs showed clinical signs of severe diarrhea. Their feces revealed large numbers of cysts consistent with Giardia sp. Therefore, we treated the dogs with secnidazole (10 mg/kg, single dose) given orally. Five days after treatment, all dogs were negative for Giardia spp. Treatment II: Three months later, the same ten Beagles again presented with diarrhea. Feces were collected, revealing Giardia sp. in all dogs. This time, we treated them with an antiprotozoan (secnidazole, 10 mg/kg dose) combined with a commercial homeopathic drug for diarrhea control (3 g dose/animal at 12 h interval). We found that three to five homeopathic doses were needed to achieve normal fecal scores in all dogs. After 5 days of treatment, stool samples had normal consistency and were negative for Giardia. This is the first record of using secnidazole to control canine giardiasis associated with homeopathic drugs to prevent diarrhea.
期刊介绍:
The Journal MVZ Córdoba is an open access international scientific journal financed and edited by the University of Córdoba (Colombia). The journal publishes quarterly, continuously in PDF, XML, Epub, original articles, literature reviews, brief communications and clinical cases, peer-reviewed (double-blind) in Spanish and English, which are related to the agricultural and veterinary sciences. The journal is directed to natural and legal persons of veterinary medicine, animal husbandry, public health, epidemiology, aquaculture, biology, basic biomedical sciences and biotechnology and constitutes a space for academic and scientific discussion around the work of professionals in Veterinary Medicine and Zootechnics. Four-monthly publication.
"The Journal MVZ Córdoba supports the policies for registration of clinical trials of the World Health Organization (WHO) and the International Committee of Medical Journal Editors (ICMJE), since it recognizes the importance of these initiatives for international registration and dissemination. of information about clinical studies, in open access. As a result, since 2007, the journal MVZ Córdoba only publishes clinical research articles that have received an identification number in one of the Clinical Trial Registries validated by the criteria established by WHO and ICMJE, whose addresses are available in the ICMJE website. The identification number is recorded at the end of the summary. "