Box-Behnken设计优化微波辅助提取不列颠菊酚类化合物

IF 16.4 1区化学 Q1 CHEMISTRY, MULTIDISCIPLINARY

Accounts of Chemical Research Pub Date : 2022-06-21 DOI:10.20450/mjcce.2022.2483

V. Ivanova, A. Trendafilova

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引用次数: 0

摘要

采用单因素实验和四个自变量（液固比、乙醇浓度、提取时间和温度）的Box-Behnken设计，研究了英国菊地上部分酚类化合物的密闭容器微波辅助提取（MAE）。方差分析结果表明，所获得的模型在95%的置信水平下是显著的。最大总酚含量（46.19 mg GAE/g DM）的提取参数为15.13 ml/g液固比、55.95%EtOH、73.74ºC和5.73分钟。与经典浸渍相比，所提出的不列颠紫苏酚类化合物的MAE节省了大量时间，提取率高。

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Optimization of microwave-assisted extraction of phenolic compounds from Inula britannica L. using the Box-Behnken design

A closed-vessel microwave-assisted extraction (MAE) of phenolic compounds from the aerial parts of Inula britannica L. using single-factor experiments and the Box-Behnken design with four independent variables (liquid-to-solid ratio, ethanol concentration, extraction time, and temperature) was investigated. The ANOVA results showed that the obtained model was significant at a 95 % confidence level. The extraction parameters for the maximal total phenolic content (46.19 mg GAE/g DM) were determined to be 15.13 ml/g liquid-to-solid ratio, 55.95 % EtOH, 73.74 ºC, and 5.73 min. Compared with classical maceration, the proposed MAE of phenolic compounds from I. britannica saves a lot of time and gives a high extraction yield.

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来源期刊

Accounts of Chemical Research 化学-化学综合

CiteScore

31.40

自引率

1.10%

发文量

312

审稿时长

2 months

期刊介绍： Accounts of Chemical Research presents short, concise and critical articles offering easy-to-read overviews of basic research and applications in all areas of chemistry and biochemistry. These short reviews focus on research from the author’s own laboratory and are designed to teach the reader about a research project. In addition, Accounts of Chemical Research publishes commentaries that give an informed opinion on a current research problem. Special Issues online are devoted to a single topic of unusual activity and significance. Accounts of Chemical Research replaces the traditional article abstract with an article "Conspectus." These entries synopsize the research affording the reader a closer look at the content and significance of an article. Through this provision of a more detailed description of the article contents, the Conspectus enhances the article's discoverability by search engines and the exposure for the research.