{"title":"HIV/AIDS孕妇母婴阻断前后相关实验室检测指标的研究进展","authors":"Guosheng Su, L. Qin, Lida Mo","doi":"10.4236/wja.2020.102013","DOIUrl":null,"url":null,"abstract":"More than 90% of HIV-positive \nchildren come from mother-to-child transmission, so mother-to-child \ninterdiction is the main measure to prevent AIDS in children. Relevant data \nshow that the incidence of mother-to-child transmission of HIV usually fluctuates \nbetween 15% and 50% without intervention. Standardized and effective \ncomprehensive intervention can reduce the transmission rate of mother to child \nto less than 1%. At present, it is believed that mother-to-child transmission \nof AIDS can be blocked by comprehensive intervention, and its mechanism has \nbeen clearly studied. Combined with highly effective antiviral treatment, safe \nlabor and artificial feeding, the mother to child transmission rate can be \nreduced to less than 1%. However, due to the effect of drugs on mother-to-child \ntransmission of AIDS may lead to some changes in the main biochemical \nindicators of mother-to-child, there is no systematic analysis of the viral \nload, T lymphocyte subsets and major biochemical indicators of HIV/AIDS pregnant \nwomen before and after maternal-to-child transmission. In this study, the viral \nload, T lymphocyte subsets and major biochemical indicators of HIV/AIDS \npregnant women before and after maternal-infant blockade were dynamically \nanalyzed. It is hoped that this study will help to observe the basic physical \nfitness and disease development of pregnant women with HIV/AIDS during \npregnancy, to provide a strong basis for the treatment and evaluation of \nmaternal-infant blockade of HIV/AIDS pregnant women, and to establish a \ncomplete set of laboratory indicators to understand the body status of pregnant \nwomen at all stages to minimize \nthe probability of fetal transmission, which will make good economic and social \nbenefits.","PeriodicalId":58633,"journal":{"name":"艾滋病(英文)","volume":" ","pages":""},"PeriodicalIF":0.0000,"publicationDate":"2020-05-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Research Progress of Related Laboratory Testing Indexes before and after Mother-Infant Blocking in HIV/AIDS Pregnant Women\",\"authors\":\"Guosheng Su, L. Qin, Lida Mo\",\"doi\":\"10.4236/wja.2020.102013\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"More than 90% of HIV-positive \\nchildren come from mother-to-child transmission, so mother-to-child \\ninterdiction is the main measure to prevent AIDS in children. Relevant data \\nshow that the incidence of mother-to-child transmission of HIV usually fluctuates \\nbetween 15% and 50% without intervention. Standardized and effective \\ncomprehensive intervention can reduce the transmission rate of mother to child \\nto less than 1%. At present, it is believed that mother-to-child transmission \\nof AIDS can be blocked by comprehensive intervention, and its mechanism has \\nbeen clearly studied. Combined with highly effective antiviral treatment, safe \\nlabor and artificial feeding, the mother to child transmission rate can be \\nreduced to less than 1%. However, due to the effect of drugs on mother-to-child \\ntransmission of AIDS may lead to some changes in the main biochemical \\nindicators of mother-to-child, there is no systematic analysis of the viral \\nload, T lymphocyte subsets and major biochemical indicators of HIV/AIDS pregnant \\nwomen before and after maternal-to-child transmission. In this study, the viral \\nload, T lymphocyte subsets and major biochemical indicators of HIV/AIDS \\npregnant women before and after maternal-infant blockade were dynamically \\nanalyzed. It is hoped that this study will help to observe the basic physical \\nfitness and disease development of pregnant women with HIV/AIDS during \\npregnancy, to provide a strong basis for the treatment and evaluation of \\nmaternal-infant blockade of HIV/AIDS pregnant women, and to establish a \\ncomplete set of laboratory indicators to understand the body status of pregnant \\nwomen at all stages to minimize \\nthe probability of fetal transmission, which will make good economic and social \\nbenefits.\",\"PeriodicalId\":58633,\"journal\":{\"name\":\"艾滋病(英文)\",\"volume\":\" \",\"pages\":\"\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2020-05-06\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"艾滋病(英文)\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://doi.org/10.4236/wja.2020.102013\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"艾滋病(英文)","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.4236/wja.2020.102013","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Research Progress of Related Laboratory Testing Indexes before and after Mother-Infant Blocking in HIV/AIDS Pregnant Women
More than 90% of HIV-positive
children come from mother-to-child transmission, so mother-to-child
interdiction is the main measure to prevent AIDS in children. Relevant data
show that the incidence of mother-to-child transmission of HIV usually fluctuates
between 15% and 50% without intervention. Standardized and effective
comprehensive intervention can reduce the transmission rate of mother to child
to less than 1%. At present, it is believed that mother-to-child transmission
of AIDS can be blocked by comprehensive intervention, and its mechanism has
been clearly studied. Combined with highly effective antiviral treatment, safe
labor and artificial feeding, the mother to child transmission rate can be
reduced to less than 1%. However, due to the effect of drugs on mother-to-child
transmission of AIDS may lead to some changes in the main biochemical
indicators of mother-to-child, there is no systematic analysis of the viral
load, T lymphocyte subsets and major biochemical indicators of HIV/AIDS pregnant
women before and after maternal-to-child transmission. In this study, the viral
load, T lymphocyte subsets and major biochemical indicators of HIV/AIDS
pregnant women before and after maternal-infant blockade were dynamically
analyzed. It is hoped that this study will help to observe the basic physical
fitness and disease development of pregnant women with HIV/AIDS during
pregnancy, to provide a strong basis for the treatment and evaluation of
maternal-infant blockade of HIV/AIDS pregnant women, and to establish a
complete set of laboratory indicators to understand the body status of pregnant
women at all stages to minimize
the probability of fetal transmission, which will make good economic and social
benefits.