{"title":"新生儿严重胎儿和轻度溶血病:母体抗E抗体的矛盾表现","authors":"Rajan V. Joshi, Shilpa U. Kalane, A. Kulkarni","doi":"10.4103/ejh.ejh_41_15","DOIUrl":null,"url":null,"abstract":"Maternal antibody production is stimulated when fetal red cells are positive for an antigen absent onmother’s red cells. Alloimmune hemolytic disease of fetus and newborn due to anti E is uncommon. We report a case of anti-E hemolytic disease in a neonate who had severe fetal and mild neonatal hemolytic manifestations. The neonate was treated with phototherapy. He also received intravenous immunoglobulin and single PCV transfusion.","PeriodicalId":42139,"journal":{"name":"Egyptian Journal of Haematology","volume":"47 1","pages":"158 - 159"},"PeriodicalIF":0.1000,"publicationDate":"2022-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Severe fetal and mild hemolytic disease of newborn: a paradoxical presentation of maternal anti-E antibody\",\"authors\":\"Rajan V. Joshi, Shilpa U. Kalane, A. Kulkarni\",\"doi\":\"10.4103/ejh.ejh_41_15\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Maternal antibody production is stimulated when fetal red cells are positive for an antigen absent onmother’s red cells. Alloimmune hemolytic disease of fetus and newborn due to anti E is uncommon. We report a case of anti-E hemolytic disease in a neonate who had severe fetal and mild neonatal hemolytic manifestations. The neonate was treated with phototherapy. He also received intravenous immunoglobulin and single PCV transfusion.\",\"PeriodicalId\":42139,\"journal\":{\"name\":\"Egyptian Journal of Haematology\",\"volume\":\"47 1\",\"pages\":\"158 - 159\"},\"PeriodicalIF\":0.1000,\"publicationDate\":\"2022-04-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Egyptian Journal of Haematology\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.4103/ejh.ejh_41_15\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q4\",\"JCRName\":\"HEMATOLOGY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Egyptian Journal of Haematology","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.4103/ejh.ejh_41_15","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q4","JCRName":"HEMATOLOGY","Score":null,"Total":0}
Severe fetal and mild hemolytic disease of newborn: a paradoxical presentation of maternal anti-E antibody
Maternal antibody production is stimulated when fetal red cells are positive for an antigen absent onmother’s red cells. Alloimmune hemolytic disease of fetus and newborn due to anti E is uncommon. We report a case of anti-E hemolytic disease in a neonate who had severe fetal and mild neonatal hemolytic manifestations. The neonate was treated with phototherapy. He also received intravenous immunoglobulin and single PCV transfusion.