鱼缸肉芽肿的临床、皮肤镜和实验室要点

D. Dobrosavljevic, B. Lukovic, D. Brasanac, O. Kosovac
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引用次数: 0

摘要

摘要在具有免疫活性的个体中,海洋分枝杆菌(M.marinum)感染通常表现为局部皮肤损伤,更为人所知的是“游泳池肉芽肿”或“鱼缸肉芽肿”(FTG)。在确定FTG的诊断时,医生在临床实践中遇到了几个问题:只有不到三分之二的活检中检测到肉芽肿,只有少数病例中检测到抗酸杆菌。大多数播散性和侵袭性FTG形式在开始时未被识别,发生在免疫抑制患者中,包括器官移植患者。据报道,肢体功能受损甚至截肢、内脏受累和致命后果。尽管全世界已经报道了1000多例FTG病例,但作为诊断辅助手段的FTG皮肤镜检查尚未报道。介绍了最近发病的FTG病例,在皮肤镜检查的指导下,从活检材料中分离和鉴定微生物,我们总结了海洋分枝杆菌感染的临床和实验室诊断要点。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Clinical, Dermatoscopical and Laboratory Essentials of Fish Tank Granuloma
Abstract In immunocompetent individuals Mycobacterium marinum (M. marinum) infection usually presents with localized skin lesions, better known as “swimming pool granuloma” or “fish tank granuloma” (FTG). When establishing the diagnosis of FTG, doctors encounter several problems in the clinical practice: granulomas are detected in less than two thirds of biopsies and acid-fast bacilli are identified only in a minority of cases. Majority of disseminated and aggressive FTG forms are unrecognized at the beginning, and occur in immunosuppressed patients, including organ transplant patients. Functional impairment or even amputation of the extremity, visceral involvement and lethal outcome have been reported. Although more than one thousand cases of FTG have been reported worldwide, dermatoscopy of FTG, as a diagnostic aid, has not been reported yet. Presenting the case of FTG of recent onset where, guided by dermatoscopy, microorganisms were isolated and identified from the biopsy material, we summarize the essentials of clinical and laboratory diagnostics of M. marinum infection.
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期刊介绍: Serbian Journal of Dermatology and Venereology is a journal of the Serbian Association of Dermatologists and Venereologists. The journal is published in English, quarterly and intended to provide rapid publication of papers in the field of dermatology and venereology. Manuscripts are welcome from all countries in the following categories: editorials, original studies, review articles, professional articles, case reports, and history of medicine.
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