A型主动脉夹层患者的双动脉插管策略:印度三级心脏中心的经验

Q4 Medicine
Archit Patel, P. Nayak, Rahul Singh, C. Doshi
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引用次数: 0

摘要

背景:升主动脉和主动脉弓手术中的插管策略是一个值得讨论的问题。大多数时间深低温停循环(DHCA)是首选策略,但它也有一些缺点。双动脉插管(DAC)可以缩短DHCA时间,避免相关的发病率和死亡率。目的:比较接受DAC急性A型夹层手术、中低温下顺行脑灌注和DHCA下单动脉插管(SAC)技术的患者对中风、癫痫发作和精神病的主要转归以及灌注不当、住院时间和死亡率的次要转归。材料和方法:本研究对2015年7月至2020年7月期间在联合国梅塔心脏病研究所CTVS科接受延伸至主动脉弓和主要血管的急性升主动脉夹层(AAD)手术的64名患者进行了回顾性分析。通过医院数据筛选,选择了30例SAC手术患者和34例DAC手术患者,并对他们的档案进行了研究和分析。所有患者均使用二维超声心动图和计算机断层扫描主动脉图进行诊断,以确认诊断。44名急诊患者在接受急诊手术前病情稳定,20名患者进行了半选择性手术。在64名患者中,40名患者使用复合机械瓣膜接受Bentall’s手术,10名患者接受升主动脉置换术,7名患者接受半弓升主动脉置换手术,2名患者接受Bentall's冠状动脉搭桥术,2名接受David’s手术、2名接受Yacoub’s手术,1例患者使用生物瓣膜进行Bentall手术。在SAC手术的30名患者中,25名患者进行了股骨插管,5名患者仅进行了右腋下插管。DAC组均行右腋动脉和股动脉插管。分析所有患者的主要和次要结果。结果:本研究共纳入64例诊断为A型AAD的患者,其解剖皮瓣延伸至主要血管。与SAC患者相比,采用DAC技术手术的患者中风、灌注不良和住院死亡率的发生率显著降低。结论:在涉及主要弓血管和股动脉的AAD中,为维持体外循环(CPB)和器官灌注,向动脉系统提供快速、安全的血液流入是至关重要的。其理念是为动脉系统提供快速、安全的血液流入,以维持体外循环(CPB)和器官灌注,这是至关重要的。右腋动脉在急性主动脉夹层中的作用最小,当插管时,可以向大脑提供不间断的流动,也可以提供足够的流入来维持CPB。除此之外,如果股动脉插管为腹部器官和下肢提供流量,将防止误灌注综合征。DAC在复杂的A型主动脉夹层和主动脉弓手术中是安全的,并且与SAC相比具有更好的围手术期结果。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Double-arterial cannulation strategy in patients presenting with Type A aortic dissection: An Indian tertiary cardiac center experience
Background: Cannulation strategies in ascending aorta and arch surgeries are a matter of immense discussion. Majority of time deep hypothermic circulatory arrest (DHCA) is the preferred strategy, but it does come with its set of demerits. Double-arterial cannulation (DAC) may decrease DHCA time and avoid its related morbidity and mortality. Aim: The aim was to compare patients undergoing surgery in acute Type A dissection by DAC with antegrade cerebral perfusion under moderate hypothermia and single-arterial cannulation (SAC) technique under DHCA with respect to the primary outcome of stroke, seizure, and psychosis and the secondary outcome as malperfusion, hospital stay, and mortality. Materials and Methods: This study was a retrospective analysis of 64 patients operated for acute ascending aortic dissection (AAD) extending into arch and major vessels in the Department of CTVS, UN Mehta Institute of Cardiology and Research between July 2015 and July 2020. After screening through the hospital data, 30 patients operated by SAC and 34 patients operated by DAC technique were selected and their files were studied and analyzed. All patients were diagnosed using two-dimensional echocardiogram and computerized tomography aortogram to confirm the diagnosis. Forty-four patients who presented to emergency were stabilized before taking up for emergency surgery and 20 were operated semi-electively. Out of 64 patients, 40 patients underwent Bentall's procedure using composite mechanical valve, 10 patients underwent ascending aorta replacement, 7 patients underwent ascending aorta replacement with hemiarch, 2 patients underwent Bentall's with coronary artery bypass grafting, 2 patients underwent David's procedure, 2 patients underwent Yacoub's procedure, and 1 patient underwent Bentall's procedure using biological valve. Out of 30 patients operated by SAC, 25 patients had femoral cannulation and 5 patients had only right axillary cannulation. In the DAC group, all had right axillary artery and femoral cannulation. All patients were analyzed for primary and secondary outcomes. Results: A total of 64 patients diagnosed with Type A AAD with dissection flap extending into major vessels were included in the study. Those patients operated with DAC technique had a significantly lower incidence of stroke, malperfusion, and hospital mortality as compared to the patients with SACs. Conclusion: In AAD involving major arch vessel and femoral arteries, the idea is to provide rapid and safe blood inflow to arterial system in order to maintain cardiopulmonary bypass (CPB) and organ perfusion, which is of utmost iimportance. The idea is to provide rapid and safe blood inflow to arterial system in order to maintain cardiopulmonary bypass (CPB) and organ perfusion, which is of utmost importance. The right axillary artery is least involved in acute aortic dissection and when cannulated can provide uninterrupted flow to brain and also provide sufficient inflow to maintain CPB. Along with this, if femoral artery cannulation provides flow to abdominal organs and lower limb, it will prevent malperfusion syndrome. DAC is safe in complex Type A aortic dissection and aortic arch surgery and has better perioperative outcomes compared to SAC.
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