重症肌无力、胸腺瘤和胸腺切除术的临床干预

S. Oyewole, D. Otohinoyi, Tolu Akinfisoye, Ibukun Oshobu, A. Babatunde, Esther Olunu, A. Fakoya
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引用次数: 1

摘要

重症肌无力是一种自身免疫性疾病,使患者处于衰弱状态。目前,每10万人口中有14至20人受到影响。其发病机制涉及胸腺淋巴细胞产生的抗体对乙酰胆碱受体的破坏。症状可能从损害眼外肌肉到全身无力不等。据报道,这些抗体还会影响体内的其他肌肉结构,如心肌细胞,导致心律失常发作,这可能是致命的。这篇综述是一个学生项目,涉及重症肌无力的评估以及胸腺瘤和胸腺切除术之间的相互作用。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Myasthenia Gravis, Thymoma, and Thymectomy: The Clinical Interplay
Myasthenia gravis is an autoimmune disorder that places patients in debilitating condition. It currently affects 14 to 20 per 100,000 population. Its pathogenesis involves the destruction of acetylcholine receptor by antibodies produced by lymphocytes in the thymus gland. Symptoms could vary from impair extraocular muscles to generalized weakness. The antibodies have also been reported to affect other muscle structure within the body such as cardiomyocytes, leading to arrhythmia episodes which could be fatal. This review is a student project and involves the assessment of myasthenia gravis and the interplay between thymoma and thymectomy.
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