药用植物对糖尿病患者胰腺β细胞的影响:伊朗人贡献的系统综述

Davood Oliaee, H. Niazkar, A. Abbasnezhad, M. Ghorbani, Parisa Sadat Alavi Shahri, Saeide Saghaee Shahri, Kasra Ghanaiyan
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引用次数: 2

摘要

引言:糖尿病是一种高患病率的代谢紊乱,约占世界人口的25%。这篇系统综述旨在评估伊朗关于药用植物对糖尿病胰腺β细胞影响的研究。方法:这项系统综述是通过在Medline、PubMed、Google Scholar和ScienceDirect等数据库中搜索进行的,直到2018年4月。这项研究发表在伊朗,经过同行评审,设计为一项针对I型糖尿病的随机对照试验,并进行了检索和筛选。结果:电子数据库的初步搜索结果产生了822篇相关文章。经过两个阶段的筛选、查阅参考文献和删除各种数据库中的重复文章,最终选择了18篇文章进行审查。结论:根据研究结果,药用植物通过多种机制对动物模型中胰腺β细胞的性能产生了积极影响,如增加β细胞的数量、大小、再生和减少炎症。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
The Effects of Medicinal Plants on Pancreatic Beta Cells in Diabetes: A Systematic Review of Iranians’ Contributions
Introduction: Diabetes mellitus (DM) is a metabolic disorder with a high prevalence, which affects approximately 25% of the world’s population. This systematic review aimed to assess the Iranian research regarding the effects of medicinal plants on pancreatic beta cells in diabetes.Methods: This systematic review was conducted via searching in databases such as Medline, PubMed, Google Scholar, and ScienceDirect until April 2018. The studied that were published in Iran, peer-reviewed, and designed as a randomized control trial on type I diabetes were retrieved and screened.Result: The initial search results of the electronic databases yielded 822 relevant articles. After two stages of screening, checking the references, and removing the duplicate articles in various databases, 18 articles were finally selected for the review.Conclusion: According to the results, medicinal plants have a positive impact on the performance of pancreatic beta cells in animal models through various mechanisms, such as increasing the number, size, regeneration, and reduction of the inflammation of beta cells.
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