美容注射治疗结核分枝杆菌感染

中华医学美学美容杂志 Pub Date : 2018-12-15 DOI:10.3760/CMA.J.ISSN.1671-0290.2018.06.014

Linying Lai, Lixia Zhang, Minliang Chen, H. Duan, Guiwen Zhou

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The patients were treated with VSD thorough surgical debridement, the bacterial type of NTM was identified by bacterial culture and PCR identification and anti-NTM drugs were systematically used according to the results of drug sensitivity. \n \n \nResults \nFourteen patients who were treated with scientific debridement surgeries combined with regular anti-NTM drug treatment in our hospital for 2-4 months were discharged after their skin lesions were cleared and healed and they were continually treated with anti-NTM drugs for 12 months. Fourteen patients were completely cured by using the above treatments without severe side effects, such as liver and kidney dysfunction, nervous system disorders and so on. Only colpitis mycotica occurred in 3 patients. In addition, one patient presented the decrease of leukopenia after using anti-NTM drugs for 2 months and continued to complete the treatment after we adjusted the treatment plan to returning the level of leukopenia to the normal. 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引用次数: 0

摘要

目的通过科学的清创手术，结合常规应用抗结核分枝杆菌药物，探讨美容注射后非结核分枝杆菌感染的诊断和治疗方法。方法2012-2016年在其他医院长期未治愈的14例化妆品注射后感染NTM的患者。对患者进行VSD彻底手术清创治疗，通过细菌培养和PCR鉴定NTM的细菌类型，并根据药物敏感性结果系统使用抗NTM药物。结果14例在我院接受科学清创手术联合常规抗NTM药物治疗2-4个月的患者，在皮肤病变清除和愈合后出院，并持续使用抗NTM药治疗12个月。14例患者通过上述治疗完全治愈，无肝肾功能障碍、神经系统紊乱等严重副作用，仅3例发生霉菌性阴道炎。此外，一名患者在使用抗NTM药物2个月后出现白细胞减少，并在我们调整治疗计划使白细胞减少水平恢复正常后继续完成治疗。对这14例患者进行了1-5年的随访，没有复发。12例患者面部外观基本正常，有轻微疤痕。2例患者面部手术面积不均，经组织移植和光电治疗，面部外形基本恢复正常。结论对于注射等侵入性操作引起的NTM患者，采用科学的清创手术和系统的靶向药物治疗相结合的综合治疗方案，不仅可以有效治愈NTM感染，而且可以最大限度地减少二次伤害，恢复患者的容貌，值得临床应用。关键词：改善容貌；注射；分枝杆菌感染，非结核；清创；药物治疗

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Treatment of mycobacterium tuberculousis induced with cosmetic injection

Objective To explore the diagnosis and treatment of non-tuberculosis mycobacteria (NTM) infection after cosmetic injection via scientific debridement surgery combined with regular application of anti-NTM drugs. Methods 14 patients who were infected with NTM after cosmetic injection and were not cured over a long period of time in other hospitals from 2012 to 2016. The patients were treated with VSD thorough surgical debridement, the bacterial type of NTM was identified by bacterial culture and PCR identification and anti-NTM drugs were systematically used according to the results of drug sensitivity. Results Fourteen patients who were treated with scientific debridement surgeries combined with regular anti-NTM drug treatment in our hospital for 2-4 months were discharged after their skin lesions were cleared and healed and they were continually treated with anti-NTM drugs for 12 months. Fourteen patients were completely cured by using the above treatments without severe side effects, such as liver and kidney dysfunction, nervous system disorders and so on. Only colpitis mycotica occurred in 3 patients. In addition, one patient presented the decrease of leukopenia after using anti-NTM drugs for 2 months and continued to complete the treatment after we adjusted the treatment plan to returning the level of leukopenia to the normal. These 14 patients were followed up for 1-5 years with no recurrence of the lesion. The facial appearance of 12 patients were almost normal with slight scars. The facial surgery area of 2 patients were uneven and nearly recovered to normal facial appearance by tissue transplantation and photoelectric therapy. Conclusions For the NTM patients caused by invasive procedures such as injection, the comprehensive treatment program, which combined scientific debridement surgery and systematically targeted drug treatment, not only can effectively cure NTM infection, but also minimize secondary injury and restore the patients' appearance, which is worthy of clinical application. Key words: Improving looks; Injections; Mycobacterium infections, nontuberculous; Debridement; Drug therapy

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来源期刊

中华医学美学美容杂志

自引率

0.00%

发文量

4641

期刊介绍： "Chinese Journal of Medical Aesthetics and Cosmetology" is a high-end academic journal focusing on the basic theoretical research and clinical application of medical aesthetics and cosmetology. In March 2002, it was included in the statistical source journals of Chinese scientific and technological papers of the Ministry of Science and Technology, and has been included in the full-text retrieval system of "China Journal Network", "Chinese Academic Journals (CD-ROM Edition)" and "China Academic Journals Comprehensive Evaluation Database". Publishes research and applications in cosmetic surgery, cosmetic dermatology, cosmetic dentistry, cosmetic internal medicine, physical cosmetology, drug cosmetology, traditional Chinese medicine cosmetology and beauty care. Columns include: clinical treatises, experimental research, medical aesthetics, experience summaries, case reports, technological innovations, reviews, lectures, etc.