空气过敏原致敏在儿童特应性皮炎中占主导地位

IF 0.2 Q4 DERMATOLOGY
HM Thilanka Seneviratne, KM K. Somaratne, Subhani Brabaharan, GDilan Dileepa Jayarathne Bandara, AR. T Vindya Alahakoon, Priyanka Senevivikrama, PV Rangith Kumarasiri
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引用次数: 0

摘要

背景:儿童特应性皮炎(AD)经常发作。正确识别引起过敏原的过敏原对管理AD很重要。怀疑食物过敏原是罪魁祸首可能会导致不必要的食物限制,从而对这些儿童的生长产生不利影响。鉴于这一事实,我们旨在评估斯里兰卡AD儿童的过敏原致敏模式。目的:评估AD儿童的食物和空气过敏原致敏模式。材料和方法:本研究对100名临床诊断为AD的儿童专科医院和三级护理医院皮肤科门诊连续患者进行。年龄从1岁到18岁不等。所有人都接受了皮肤点刺试验(SPT),使用了针对屋尘螨、翼纹皮螨(HDM-DP)、烟曲霉(AF)、猫上皮细胞(CE)、牛奶(CM)、蛋清(EW)和花生的点刺试验溶液。结果:100例患者中HDM-DP SPT阳性率为53.0%。CE阳性率为15.0%,AF阳性率为9.0%。以上三者均为空气过敏原,CM、EW和花生的食物过敏原敏感性分别为9.0%、2.0%和1.0%。值得注意的是,HDM-DPSPT的风团大小与受试者的年龄有很强的相关性(R2=0.0723,P=0.007)。HDM-DP的风团大小与年龄呈正相关。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Aeroallergen sensitization predominates in children with atopic dermatitis
Background: Children with atopic dermatitis (AD) suffer from frequent flare-ups. Correct identification of allergens responsible for flare-ups is important in managing AD. Suspecting food allergens as culprits may result in unnecessary food restrictions which adversely affect the growth of these children. In view of this fact, we aimed to assess the allergen sensitization pattern of children with AD in Sri Lanka. Objective: The objective is to assess the food and aeroallergen sensitization pattern of children with AD. Materials and Methods: This study was conducted among 100 consecutive patients refereed to the dermatology clinics of a specialized children's hospital and a tertiary care hospital with the clinical diagnosis of AD. Age ranged from 1 to 18 years. All underwent a Skin prick test (SPT), using prick test solutions for house dust mite Dermatophagoids pteronyssinus (HDM-DP), Aspergillus fumigatus (AF), cat epithelia (CE), cow's milk (CM), egg white (EW), and peanut. Results: Of 100 patients 53.0% had positive SPT for HDM-DP. 15.0% were positive for CE, 9.0% positive for AF. All above three are aeroallergens, food allergen sensitivities were 9.0% for CM, 2.0% for EW, and 1.0% for peanuts. It is of note that the wheal size of HDM-DP SPT showed a very strong correlation with the age of the subject (R2 = 0.0723, P = 0.007). Conclusion: Aeroallergen sensitization predominate over food allergen sensitization in children with AD. HDM and CE were the most common aeroallergen sensitivities. The wheal size of HDM-DP had a very strong positive correlation with age.
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