立陶宛引种青蒿药用原料的酚类含量及抗氧化活性

IF 0.5 4区化学 Q4 CHEMISTRY, MULTIDISCIPLINARY

Chemija Pub Date : 2023-04-07 DOI:10.6001/chemija.2023.34.1.6

S. Saunoriūtė, O. Ragažinskienė, L. Raudonė, L. Ivanauskas, M. Marksa

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引用次数: 0

摘要

在过去的十年里，人们特别关注蒿属植物，以及将其药用原料用于治疗目的的可能性。本研究的目的是测定四种引种蒿药材中酚类化合物的变异性，并评价提取物的体外抗氧化活性。用分光光度法测定的青蒿药材中酚类化合物（297.37±9.18 mg RE/g DW）和黄酮类化合物（77.73±7.40 mg RE/g DW）的总量最高。采用高效液相色谱法对蒿提取物样品中的个别酚类物质进行了定性和定量分析。在所研究的提取物中，主要的酚类化合物是绿原酸和3,5-二咖啡酰基奎宁酸。结果表明，青蒿药材的甲醇提取物具有最强的抗自由基和还原性能。

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Phenolic content and antioxidant activity in medicinal raw material of introduced Artemisia L. species in Lithuania

In the last decade, special attention has been paid to Artemisia (L.) genus plants, the possibilities of using their medicinal raw material for therapeutic purposes. The aim of the research was to determine the variability of the phenolic compounds in the medicinal raw material of four introduced Artemisia L. species and to evaluate the antioxidant activity of extracts in vitro. The highest total amount of phenolic compounds (297.37±9.18 mg RE/g DW) and flavonoids (77.73±7.40 mg RE/g DW) evaluated via spectrophotometry was detected in Artemisia annua L. medicinal raw material samples. Qualitative and quantitative analysis of individual phenolics in the samples of Artemisia extracts was carried out by applying the HPLC method. In the studied extracts, the predominant phenolic compounds were chlorogenic acid and 3,5-dicaffeoylquinic acid. It was determined that the methanol extracts of A. annua medicinal raw material have the strongest antiradical and reducing properties.

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来源期刊

Chemija 化学-化学综合

CiteScore

1.30

自引率

16.70%

发文量

审稿时长

>12 weeks

期刊介绍： Chemija publishes original research articles and reviews from all branches of modern chemistry, including physical, inorganic, analytical, organic, polymer chemistry, electrochemistry, and multidisciplinary approaches.