预测原发性二尖瓣反流患者二尖瓣矫正术后更好功能结果的最新超声心动图参数

Indah Puspita, A. Soesanto, E. Rudiktyo, R. Ariani, A. Kuncoro
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引用次数: 1

摘要

摘要目的我们分析了一些超声心动图参数是否能很好地预测二尖瓣矫正术后的功能结果。背景射血分数不是决定最佳手术时间的唯一参数,也不是术后功能改善的指标。严重程度测量是手术决策的主要考虑因素。手术后左心室缩小反映了更好的功能结果。方法在2019年,67名患者被纳入本分析。年龄53岁(17-67岁),男性52.2%。所有患者都有严重的原发性二尖瓣反流,并接受二尖瓣手术(二尖瓣修复或置换)治疗。进行回顾性超声心动图分析,以找到预测术后更好功能结果的最佳参数。结果数据收集于2019年1月至12月。在Harapan Kita国家心脏中心接受的262例原发性二尖瓣手术中,有67名患者被纳入,另一名患者因继发性二尖瓣反流机制、合并先天性心脏病和/或其他重大瓣膜疾病的可能性而被排除在外,由于之前医院的转诊流程以及用于进一步分析的超声心动图视图不完整,导致术后数据缺失。在双变量分析中,舒张末期容积(EDV)和反流容积(RV)是术后左心室直径减小的有力预测因素(p 0.0001和p 0.05)。如果进行手术,舒张末期容积133,5ml或更大可预测左心室直径的减小(敏感性87.3%,敏感性66.7%)原发性二尖瓣手术的其他超声心动图参数。在决定手术时机之前测量EDV将有助于在手术后获得更好的功能结果。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Recent Echocardiography Parameters for Predicting Better Functional Result after Mitral Valve Correction Surgery in Patients with Primary Mitral Regurgitation
Abstract   Objectives We analyzed whether some echocardiographic parameters are good predictors of functional result after mitral valve correction surgery.    Background Ejection fraction was not the only parameter to decide optimal time for surgery, nor an indicator for a better functional result after surgery. Severity measurement being a main consideration in surgery decision. Reduced left ventricle dimension after surgery reflect a better functional result.   Methods In 2019, 67 patients was included in this analysis. Age 53 (17-67) years, male 52,2%. All patients are with severe primary mitral regurgitation and treated by mitral valve surgery (mitral valve repair or replacement). Retrospective echocardiographic analysis was performed, to find the best parameter for predicting better functional outcome after surgery.   Results Data was collected from January to December 2019. From 262 primary mitral valve surgery underwent in National Heart Center Harapan Kita, there was 67 patients included, the other was excluded due to probability of secondary mitral regurgitation mechanism, concomitant congenital heart disease and or other significant valves disease, missing post-surgery data due to referral flow to the prior hospital and less complete echocardiographic views for further analysis. In bivariate analysis, end-diastolic volume (EDV) and regurgitant volume (RV) were strong predictor of decreasing left ventricle diameter after surgery (p 0.0001 and p 0.05). End-diastolic volume 133,5 ml or more is predictive for decreasing left ventricle diameter if surgery was conducted (sensitivity 87.3%, sensitivity 66.7%).       Conclusions EDV and RV found to be good predictors for functional outcome of primary mitral valve surgery than other echocardiographic parameters. Measuring EDV before deciding timing of surgery will be helpful in targeting better functional result after surgery.    
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