Oncocardiology: Far beyond the cardiotoxicity

CVD in cancer patients can precede the diagnosis of cancer or can be related to the malignancy itself or its therapy. Many cardiovascular phenotypes have been identi ied as common across different cancer treatments. Lipshultz, et al. [6] found that survivors of childhood cancer, regardless of exposure to cardiotoxic treatments, had cardiovascular abnormalities related not only to abnormal left ventricular structure and function but also to increased traditional risk factors for atherosclerotic disease and systemic in lammation. Most recently, the relationship between atrial ibrillation (AF) and Stroke/ transient ischemic attacks (TIA) in cancer patients was conducted in a case-control study, the CHA2DS2-VASc score, which components such as heart failure, hypertension, old age, and diabetes mellitus were found to be associated with stroke in the general population, signi icantly increases the risk of stroke in cancer patients regardless of the presence of AF [7].