ECMO在多器官衰竭和长时间心肺复苏中的可能作用:亚磷酸铝中毒

M. Daliri, S. Hosseini, A. Amin, Ziae Totonchi, J. Schmitto, N. Naderi, Mona Yadollahi
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引用次数: 1

摘要

简介:磷化铝(ALP)是最常见的中毒原因之一。此外,它通常被用来企图自杀。体外膜肺氧合(ECMO)是一种支持心肺功能的治疗方法,给身体足够的时间排毒和改善器官功能;因此,使用ECMO处理问题对这些患者来说至关重要,并增加了生存机会。此外,在新冠肺炎大流行期间,新冠肺炎对治疗过程的影响以及患者对病毒的参与和接触是一个后果未知的关键问题。病例介绍:患者为一名18岁女孩,因磷酸铝中毒住院治疗。在心肺复苏过程中,ECMO被连接到患者身上。然后,患者被送往专门的医疗机构。到达时,EF(射血分数)小于5%。在中毒过程中,患者出现ARDS、暴发性肝炎、大量胃肠道和阴道出血以及败血症。ECMO在第5天断奶,当时EF报告为55%。在下文中,当患者被怀疑患有新冠肺炎时,她的全身和肺部状况加剧。采取了必要的治疗措施,患者在45天后出院。结论:ECMO是治疗ALP中毒患者的有效方法。在谨慎管理的情况下,它可以用于多器官受累和延长PCR。考虑到新冠肺炎大流行,在治疗期间注意重症监护室感染新冠肺炎的机会是非常重要的。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Possible role of ECMO in multiorgan failure and prolonged CPR: Aluminum Phosphide poisoning
Introduction: Aluminum phosphide (ALP) is one of the most common causes of poisoning. Also, it is commonly used to attempt suicide. Extracorporeal Membrane Oxygenation (ECMO) is a therapeutic method that supports the function of the heart and lungs, giving body enough time for detoxification and organ function improvement; therefore, management of the problem using ECMO is critical in these patients and increases the survival chance. Moreover, the impact of COVID-19 on the treatment course during the COVID-19 pandemic and the patients' involvement and contact with the virus is a critical issue with unknown consequences. Case presentation: The patient was an 18-year-old girl who was hospitalized due to the poisoning aluminum phosphate. The ECMO was connected to the patient during CPR. Then, the patient was transported to a specialized healthcare facility. At the time of arrival, the EF (Ejection Fraction) was less than 5%. During the course of poisoning, the patient developed ARDS, fulminant hepatitis, massive gastrointestinal and vaginal bleeding, and septicemia. The ECMO was weaned on day 5 when the EF was reported 55%. In the following, the general and pulmonary conditions of the patient exacerbated when she was suspected of having COVID-19. The necessary therapeutic measures were done and finally, the patient was discharged after 45 days. Conclusion: ECMO is a useful therapeutic procedure in ALP poisoned patients. In case of careful management, it can be used in multiple organ involvement and prolonged PCR. Considering the COVID-19 pandemic, it is very important to notice the chance of COVID-19 infection in ICU during treatment.
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来源期刊
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审稿时长
12 weeks
期刊介绍: Asia Pacific Journal of Medical Toxicology (APJMT) aims to expand the knowledge of medical toxicology and tries to provide reliable information in this field for medical and healthcare professionals. APJMT mainly focuses on research related to medical toxicology issues in the Asia Pacific region and publishes articles on clinical and epidemiological aspects of toxicology, poisonings emergency care, addiction, drug interactions and adverse effects. The journal accepts and welcomes high quality papers in the form of original articles and rarely review articles, case reports and scientific letters relevant to medical practice in toxicology.
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