我们的宝宝,你的子宫——尼日利亚西南部一家私人生育中心对代孕的回顾性研究

M. Aderonmu, Adebisi N. Oyero, O. B. Shote, Chinelo G. Okonkwo, O. Ashiru
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摘要

引言:体外受精是一种辅助生殖技术,在过去的3-5年里,它在不孕不育的管理中不断发展,现在已经扩展到包括第三方生殖解决方案。妊娠代孕有两种类型:(1)完全代孕(女性的卵子与精子受精,然后将胚胎植入另一位女性体内)或(2)部分代孕(男性的精子用于使胚胎移植到的同一位女性的卵子受精)。在尼日利亚,尽管代孕正在实施,但关于代孕结果的出版物却很少。在拉各斯Ikeja医学艺术中心,我们只进行完全代孕,也被称为妊娠代孕。研究设计:这是一项回顾性描述性研究,对2015年1月1日至2021年4月30日期间在尼日利亚西南部一家私人运营的单点生育中心进行的76个月的61个周期进行了研究。数据是从委托父母和妊娠携带者的电子医疗记录中提取的。结果:该项目共有58名妊娠期携带者。11人(19%)流产,有63名活产婴儿,其中14对双胞胎(44%),1对三胞胎(~5%),其余为单身。一名(1.7%)代孕者因产后出血而分娩并进行子宫切除术。没有产妇死亡。选择代孕最常见的原因是多次失败的体外受精周期、子宫因素不孕和高龄产妇。结论:对于想要孩子的人来说,妊娠代孕是一种有效的医学辅助生殖选择。这一选择应继续得到尼日利亚现有的道德、监管和法律框架的支持。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Our bab(y)ies, your uterus—a retrospective study on surrogacy at a private fertility center in South West Nigeria
Introduction: In vitro fertilization, a form of assisted reproductive technology has evolved over the last 3–5 decades in the management of infertility and now has been expanded to include third-party reproductive solutions. There are 2 types of gestational surrogacy: (1) full surrogacy (an egg from a woman is fertilized with a sperm and the resulting embryo is implanted into another woman) or (2) partial surrogacy (sperm from a man is used to fertilize an egg from the same woman in whom the embryo will be transferred to). In Nigeria, there is a paucity of publications on the outcomes of surrogate pregnancies, even though it is being practiced. At the Medical Art Center Ikeja Lagos, we practice only full surrogacy, otherwise referred to as gestational surrogacy. Study design: This was a retrospective descriptive study of 61 cycles performed over 76 months between January 1, 2015 and April 30, 2021 at a private-run single-location fertility center in South West Nigeria. Data were extracted from the electronic medical records of the commissioning parents and the gestational carrier. Results: There were a total of 58 gestational carriers in the program. Eleven (19%) had a miscarriage and there were 63 live births, out of which were 14 twin pairs (44%), 1 set of triplets (~5%) and the rest were singletons. One (1.7%) surrogate had delivery complicated by a hysterectomy on account of postpartum hemorrhage. There was no maternal mortality. The commonest reason for choosing surrogacy was multiple failed in vitro fertilization cycles, uterine factor infertility, and advanced maternal age. Conclusion: Gestational surrogacy is a valid medically assisted reproduction option for individuals who desire to have children. This option should continue to be supported by ethical, regulatory, and legal frameworks available in Nigeria.
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