体重指数与非酒精性脂肪肝的相关性研究

Abdulhadi Alrubaie, R. E. Rezqallah, M. A. Ahmed, S. Musa, Maitham H Al-Qanbar
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引用次数: 0

摘要

背景:非酒精性脂肪肝(NAFLD)是全球最常见的肝脏疾病。全世界的流行率为25%,广泛分布在不同的人群和地区。据报道,中东的发病率最高(32%)。由于现代生活方式和饮食,NAFLD患者的数量持续增加。这一增长发生的同时,全世界被认为肥胖的人数也在增加。通过分析脂肪肝的危险因素,研究发现,体重指数是评估肥胖的最经典的流行病学指标之一,与脂肪肝的风险相关。目的:评估年龄、性别和体重指数(BMI)作为NAFLD的危险因素。受试者和方法:这是一项从2020年9月到2021年6月的病例对照横断面研究,包括研究期间咨询肥胖研究和治疗单位的所有肥胖患者。记录年龄和性别,计算所有患者的体重指数,并将其分为BMI<25kg/m2的正常、BMI 25-30kg/m2的超重和BMI>30kg/m2的肥胖,对其进行超声检查以诊断脂肪肝变化,分为三级;结果:本研究共纳入192例患者,年龄18-55岁,平均38.09岁,男性48例,女性144例。严重NAFLD在2.8%的肥胖女性和5.5%的肥胖男性中存在,在正常和超重个体中为0%。结论:随着BMI和年龄的增加,NAFLD在所有性别中都更为普遍。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Correlation between Body Mass Index and Nonalcoholic Fatty Liver Disease
Background: Non-alcoholic fatty liver disease (NAFLD) is the most common liver disorder globally. The prevalence is 25% worldwide, distributed widely in different populations and regions. The highest rates are reported for the Middle East (32%). Due to modern lifestyles and diet, there has been a persistent increase in the number of NAFLD patients. This increase occurred at the same time  where there were also increases in the number of people considered being obese all over the world. By analyzing fatty liver risk factors, studies found that body mass index, one of the most classical epidemiological indexes assessing obesity, was associated with the risk of fatty liver. Objectives: To assess age, sex, and body mass index (BMI) as risk factors in NAFLD. Subjects and Methods: It is a case-control cross-sectional study from September 2020 till June 2021  which included all obese patients consulted the obesity research and therapy unit during the period of the study. Age and sex were recorded, body mass indices were calculated for all patients and categorized into normal with BMI < 25kg/m2, overweight with BMI 25-30 kg/m2, and obese with BMI > 30 kg/m2, ultrasonography was done to them to diagnose fatty liver changes which were categorized into three grades; mild, moderate and severe Results: 192 patients were enrolled in the study with an age range from 18-55 years with a mean of 38.09, males were 48 and females were 144. Sever NAFLD is present in 2.8% of obese females and 5.5% of obese male with 0% in normal and overweight individuals. Conclusion: NAFLD was more prevalent with increasing BMI and age in all sexes.
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