18F-FDG PET/CT在结直肠癌肝转移诊断和治疗中的价值

中华核医学与分子影像杂志 Pub Date : 2019-09-25 DOI:10.3760/CMA.J.ISSN.2095-2848.2019.09.014

Wu-jian Mao

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引用次数: 0

摘要

18F-氟脱氧葡萄糖（FDG）PET/CT对结直肠癌癌症肝转移（CRCLM）具有良好的敏感性和特异性诊断性能，可以全面识别肝外转移的存在，为治疗决策提供有价值的信息。18F-FDG PET/CT也可用于CRCLM治疗反应的早期评估和生存预测。然而，PET/CT对直径在10mm以内或化疗强烈抑制活性的病变的诊断价值有限。PET与增强CT相结合可能对提高CRCLM的诊断敏感性具有潜在价值。关键词：结直肠肿瘤；肿瘤转移；肝脏；正电子发射断层扫描；层析成像，X射线计算机；脱氧葡萄糖

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Value of 18F-FDG PET/CT in the diagnosis and treatment of colorectal cancer liver metastases

18F-fluorodeoxyglucose (FDG) PET/CT offers excellent diagnostic performance on colorectal cancer liver metastases(CRCLM) in terms of sensitivity and specificity, and can comprehensively identify the presence of extrahepatic metastases and provide valuable information for the treatment decision making. 18F-FDG PET/CT can also be used in the early assessment of response to CRCLM therapy and survival prediction. However, the diagnostic value of PET/CT is limited for lesions with diameter within 10 mm or with activity inhibited strongly by chemotherapy. PET combined with contrast enhanced CT may have potential value in improving diagnostic sensitivity for CRCLM. Key words: Colorectal neoplasms; Neoplasm metastasis; Liver; Positron-emission tomography; Tomography, X-ray computed; Deoxyglucose

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来源期刊

中华核医学与分子影像杂志核医学，分子影像

自引率

0.00%

发文量

5088

期刊介绍： Chinese Journal of Nuclear Medicine and Molecular Imaging (CJNMMI) was established in 1981, with the name of Chinese Journal of Nuclear Medicine, and renamed in 2012. As the specialized periodical in the domain of nuclear medicine in China, the aim of Chinese Journal of Nuclear Medicine and Molecular Imaging is to develop nuclear medicine sciences, push forward nuclear medicine education and basic construction, foster qualified personnel training and academic exchanges, and popularize related knowledge and raising public awareness. Topics of interest for Chinese Journal of Nuclear Medicine and Molecular Imaging include: -Research and commentary on nuclear medicine and molecular imaging with significant implications for disease diagnosis and treatment -Investigative studies of heart, brain imaging and tumor positioning -Perspectives and reviews on research topics that discuss the implications of findings from the basic science and clinical practice of nuclear medicine and molecular imaging - Nuclear medicine education and personnel training - Topics of interest for nuclear medicine and molecular imaging include subject coverage diseases such as cardiovascular diseases, cancer, Alzheimer’s disease, and Parkinson’s disease, and also radionuclide therapy, radiomics, molecular probes and related translational research.