用于生物医学成像的扩展焦深硒化锌微透镜阵列的光学设计与制造

IF 3.3 Q3 NANOSCIENCE & NANOTECHNOLOGY
Neha Khatri, S. Berwal, K. Manjunath, Bharpoor Singh
{"title":"用于生物医学成像的扩展焦深硒化锌微透镜阵列的光学设计与制造","authors":"Neha Khatri, S. Berwal, K. Manjunath, Bharpoor Singh","doi":"10.37819/nanofab.008.293","DOIUrl":null,"url":null,"abstract":"Optical coherence tomography is a well-known technique for the optical imaging biological tissues. However, the depth scanning range of high-resolution optical coherence tomography is restricted by its depth of focus. In this study, a Zinc Selenide (ZnSe) Microlens Array (MLA) is employed to overcome the depth-of-focus limitation of optical coherence tomography. The ZnSe material with a low Abbe number and high chromatic dispersion extends the depth of focus with transverse resolution. The ZnSe MLA focused the incident light (from visible to near-infrared (NIR) region) on multiple focal planes with the uniform distribution of light over a biological tissue. The MLA is designed using Zemax OpticStudio software and fabricated via a single-point diamond-turning based on Slow Tool Servo (STS) configuration. STS machining has the unique advantage of offering larger degrees of freedom with no additional baggage, thereby reducing the setup time. The experimental results show the effectiveness of the STS machining process in fabricating ZnSe MLA with desired accuracies. The characterization of fabricated MLA using Coherence Correlation Interferometry (CCI) depicts uniform lenslets with no structural and positional distortion, with a total error of 32 nm within the tolerance limit.","PeriodicalId":51992,"journal":{"name":"Nanofabrication","volume":" ","pages":""},"PeriodicalIF":3.3000,"publicationDate":"2023-02-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"1","resultStr":"{\"title\":\"Optical design and fabrication of zinc selenide microlens array with extended depth of focus for biomedical imaging\",\"authors\":\"Neha Khatri, S. Berwal, K. Manjunath, Bharpoor Singh\",\"doi\":\"10.37819/nanofab.008.293\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Optical coherence tomography is a well-known technique for the optical imaging biological tissues. However, the depth scanning range of high-resolution optical coherence tomography is restricted by its depth of focus. In this study, a Zinc Selenide (ZnSe) Microlens Array (MLA) is employed to overcome the depth-of-focus limitation of optical coherence tomography. The ZnSe material with a low Abbe number and high chromatic dispersion extends the depth of focus with transverse resolution. The ZnSe MLA focused the incident light (from visible to near-infrared (NIR) region) on multiple focal planes with the uniform distribution of light over a biological tissue. The MLA is designed using Zemax OpticStudio software and fabricated via a single-point diamond-turning based on Slow Tool Servo (STS) configuration. STS machining has the unique advantage of offering larger degrees of freedom with no additional baggage, thereby reducing the setup time. The experimental results show the effectiveness of the STS machining process in fabricating ZnSe MLA with desired accuracies. The characterization of fabricated MLA using Coherence Correlation Interferometry (CCI) depicts uniform lenslets with no structural and positional distortion, with a total error of 32 nm within the tolerance limit.\",\"PeriodicalId\":51992,\"journal\":{\"name\":\"Nanofabrication\",\"volume\":\" \",\"pages\":\"\"},\"PeriodicalIF\":3.3000,\"publicationDate\":\"2023-02-08\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"1\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Nanofabrication\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.37819/nanofab.008.293\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q3\",\"JCRName\":\"NANOSCIENCE & NANOTECHNOLOGY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Nanofabrication","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.37819/nanofab.008.293","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"NANOSCIENCE & NANOTECHNOLOGY","Score":null,"Total":0}
引用次数: 1

摘要

光学相干断层扫描是一种众所周知的生物组织光学成像技术。然而,高分辨率光学相干层析成像的深度扫描范围受到其聚焦深度的限制。在本研究中,采用硒化锌(ZnSe)微透镜阵列(MLA)来克服光学相干断层扫描的焦深限制。具有低阿贝数和高色散的ZnSe材料以横向分辨率扩展了焦深。ZnSe-MLA将入射光(从可见光到近红外(NIR)区域)聚焦在多个焦平面上,光在生物组织上均匀分布。MLA使用Zemax OpticStudio软件设计,并通过基于慢工具伺服(STS)配置的单点金刚石车削制造。STS机加工具有独特的优点,即无需额外的行李即可提供更大的自由度,从而减少设置时间。实验结果表明,STS加工工艺在制备ZnSe MLA方面具有良好的精度。使用相干相关干涉术(CCI)对制造的MLA进行表征,描绘了没有结构和位置失真的均匀小透镜,总误差在公差限度内为32nm。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Optical design and fabrication of zinc selenide microlens array with extended depth of focus for biomedical imaging
Optical coherence tomography is a well-known technique for the optical imaging biological tissues. However, the depth scanning range of high-resolution optical coherence tomography is restricted by its depth of focus. In this study, a Zinc Selenide (ZnSe) Microlens Array (MLA) is employed to overcome the depth-of-focus limitation of optical coherence tomography. The ZnSe material with a low Abbe number and high chromatic dispersion extends the depth of focus with transverse resolution. The ZnSe MLA focused the incident light (from visible to near-infrared (NIR) region) on multiple focal planes with the uniform distribution of light over a biological tissue. The MLA is designed using Zemax OpticStudio software and fabricated via a single-point diamond-turning based on Slow Tool Servo (STS) configuration. STS machining has the unique advantage of offering larger degrees of freedom with no additional baggage, thereby reducing the setup time. The experimental results show the effectiveness of the STS machining process in fabricating ZnSe MLA with desired accuracies. The characterization of fabricated MLA using Coherence Correlation Interferometry (CCI) depicts uniform lenslets with no structural and positional distortion, with a total error of 32 nm within the tolerance limit.
求助全文
通过发布文献求助,成功后即可免费获取论文全文。 去求助
来源期刊
Nanofabrication
Nanofabrication NANOSCIENCE & NANOTECHNOLOGY-
自引率
10.30%
发文量
13
审稿时长
16 weeks
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
确定
请完成安全验证×
copy
已复制链接
快去分享给好友吧!
我知道了
右上角分享
点击右上角分享
0
联系我们:info@booksci.cn Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术官方微信