我承认我生活过

Q4 Medicine
Ricardo Iglesias
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引用次数: 0

摘要

在阅读了ReSCAR,(1)在阿根廷各中心进行的有趣的急性冠状动脉综合征登记后,我脑海中浮现出一份40多年来治疗和研究该临床实体的经验汇编。这些年来,已经进行了几项随机和观察性研究(后者是由住院医生通过CONAREC注册中心率先进行的),目的是解决不同类型的ACS。尽管有最具体的诊断方法以及介入和药物治疗的进展,但我的第一个想法是,每次我与ACS患者打交道时,我仍然对最佳治疗方法心存疑虑。ACSs是一组在人群中发病率较高的临床实体,包括常见的心前区疼痛的不同临床状况。在我看来,最大的困难不是诊断,而是对每个患者的个体风险进行分类,因为它是一个不稳定的临床实体,由于复杂的病理生理基础,很难评估。与以前只关注单一临床表现(不稳定型心绞痛[UA]、非ST段抬高型心肌梗死[NSTEMI]或ST段抬高性心肌梗死[STEMI])的登记相比,ReSCAR登记提供了关于ACS整个广谱的详细信息。缺血性心脏病是我国死亡的主要原因,导致缺血性心脏病的因素没有改变。自战略-SIA登记以来的20多年里,从2001年到现在,缺乏对冠状动脉危险因素的控制与ACS(60%以上的患者患有高血压[HT],25%以上的患者患糖尿病[DM],50%以上的患者出现血脂异常,40%以上的患者现在或过去吸烟)之间的密切关系一直在令人担忧地重复。(2)
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Confieso que he vivido
After reading ReSCAR, (1) the interesting Registry on Acute Coronary Syndromes (ACS) carried out in centers of Argentina, a compendium of experiences gained in more than 40 years of treating and studying this clinical entity came to my mind. Over these years, several randomized and observational studies have been conducted (the latter were pioneered by resident physicians through the CONAREC registries), with the aim of addressing the different types of ACS. Despite the most specific diagnostic methods and advances in interventional and pharmacological therapies, my first thought is that every time I am dealing with a patient with ACS, I still have doubts about the optimal treatment. ACSs are a group of clinical entities with a high prevalence in the population and include different clinical conditions that have precordial pain in common. From my point of view, the greatest difficulty is not the diagnosis, but the categorization of each patient’s individual risk, since it is a clinical entity of erratic course and difficult to evaluate, because of a complex pathophysiological substrate. The ReSCAR registry provides detailed information on the entire broad spectrum of ACS, as opposed to previous registries that only focused on a single clinical presentation (unstable angina [UA], non-ST-elevation myocardial infarction [NSTEMI] or ST-elevation myocardial infarction [STEMI]). Ischemic heart disease is the leading cause of death in our country, and the factors that lead to it remain unchanged. In more than 20 years since the STRATEG-SIA registry, from 2001 to the present, the strong relationship between the lack of control of coronary risk factors and ACS (hypertension [HT] in more than 60% of patients, diabetes [DM] in more than 25%, dyslipidemia in more than 50%, current or past smoking in more than 40%) has been worryingly repeated. (2)
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来源期刊
Revista Argentina de Cardiologia
Revista Argentina de Cardiologia Medicine-Cardiology and Cardiovascular Medicine
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