早产儿支气管肺发育不良生物标志物的研究进展与展望

中国小儿急救医学 Pub Date : 2019-12-20 DOI:10.3760/CMA.J.ISSN.1673-4912.2019.12.011

Yu-qing Pan

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引用次数: 0

摘要

支气管肺发育不良（BPD）是早产儿最严重的肺部疾病之一，也是早产儿死亡的重要原因。BPD的病理生理机制尚不清楚。针对这种疾病的预防性和针对性治疗策略也非常有限。然而，在血液、肺泡灌洗液、呼出气体冷凝液和尿液中发现了各种生物标志物。它用于早期识别患有BPD的高危儿童，并预测疾病的严重程度和预后。关键词：生物标志物；支气管肺发育不良；早产

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Progress and prospects of biomarkers of bronchopulmonary dysplasia in premature infants

Bronchopulmonary dysplasia(BPD)is one of the most serious lung diseases in premature infants and an important cause of death in preterm infants.The pathophysiological mechanism of BPD is still unclear.The preventive and targeted treatment strategies for this disease are also very limited.However, various biomarkers have been found in blood, alveolar lavage fluid, exhaled gas condensate, and urine.It is used to identify high-risk children with BPD early and to predict the severity and prognosis of the disease. Key words: Biomarker; Bronchopulmonary dysplasia; Premature

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来源期刊

中国小儿急救医学

自引率

0.00%

发文量

6226

期刊介绍： Chinese Journal of Neurology was established in 1955, the predecessor of which is Chinese Journal of Neurology and Psychiatry. Chinese Journal of Neurology and Psychiatry has been indexed by MEDLINE until 1996, when it was divided into two journals, Chinese Journal of Neurology, and Chinese Journal of Psychiatry. Chinese Journal of Neurology is now indexed by EM, SCOPUS, AJ, WPRIM, CNKI, Wanfang Data, CSCD, etc. The impact factor of the journal is 2.755 in 2017, ranking the first among all neurological and psychological journals in China and among all the 142 medical journals published by the Chinese Medical Association. The journal is available both in print and online.