{"title":"糖尿病神经性疼痛的内源性调节取决于体育锻炼的强度:一个简短的交流","authors":"William Pereira Valadares, D. L. de Almeida","doi":"10.31579/2640-1045/085","DOIUrl":null,"url":null,"abstract":"The opioidergic systems play a key role in endogenous modulation of neuropathic pain, given that Naloxone, a nonselective opioid receptors antagonist at a dose of 100 µg, reverted the antihyperalgesia caused by physical exercise demonstrated in our previous study. Due to the lack of relates regarding the control variables of physical exercise and endogenous modulation in neuropathic diabetic pain, we investigated if such modulation is exercise intensity dependent.","PeriodicalId":72909,"journal":{"name":"Endocrinology and disorders : open access","volume":" ","pages":""},"PeriodicalIF":0.0000,"publicationDate":"2021-09-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Diabetic Neuropathic Pain has Endogenous Modulation Depending on the Intensity of Physical Exercise: A Brief Communication\",\"authors\":\"William Pereira Valadares, D. L. de Almeida\",\"doi\":\"10.31579/2640-1045/085\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"The opioidergic systems play a key role in endogenous modulation of neuropathic pain, given that Naloxone, a nonselective opioid receptors antagonist at a dose of 100 µg, reverted the antihyperalgesia caused by physical exercise demonstrated in our previous study. Due to the lack of relates regarding the control variables of physical exercise and endogenous modulation in neuropathic diabetic pain, we investigated if such modulation is exercise intensity dependent.\",\"PeriodicalId\":72909,\"journal\":{\"name\":\"Endocrinology and disorders : open access\",\"volume\":\" \",\"pages\":\"\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2021-09-16\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Endocrinology and disorders : open access\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.31579/2640-1045/085\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Endocrinology and disorders : open access","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.31579/2640-1045/085","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Diabetic Neuropathic Pain has Endogenous Modulation Depending on the Intensity of Physical Exercise: A Brief Communication
The opioidergic systems play a key role in endogenous modulation of neuropathic pain, given that Naloxone, a nonselective opioid receptors antagonist at a dose of 100 µg, reverted the antihyperalgesia caused by physical exercise demonstrated in our previous study. Due to the lack of relates regarding the control variables of physical exercise and endogenous modulation in neuropathic diabetic pain, we investigated if such modulation is exercise intensity dependent.