Darier-White病伴感觉神经性听力损失一例报告

Q4 Medicine

Rwanda Medical Journal Pub Date : 2022-06-30 DOI:10.4314/rmj.v79i2.1

E. Henshaw, H. Ekpenyong, L. E. Ekafor

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引用次数: 0

摘要

Darier-White病（毛囊角化病）是一种罕见的常染色体显性遗传性皮肤病，其特征是脂溢区角化过度的丘疹和斑块，通常表现为指甲异常，偶尔还会出现粘膜变化。它与神经认知/精神疾病、强直性脊柱炎、化脓性汗炎和肾炎有关。受影响的个体也有增加皮肤感染的趋势。然而，彻底的文献检索显示，与感音神经性听力损失没有关联。我们在此报告一例34岁的尼日利亚男子，他患有与脊椎关节病和感音神经性听力损失相关的Darier-White病（DWD）。我们确认，早期诊断、及时和适当的治疗以及充分的患者教育可以避免不良结果。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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Darier-White Disease with Sensorineural Hearing Loss – A Case Report

Darier-White disease (keratosis follicularis) is a rare autosomal dominant genodermatosis characterized by hyperkeratotic papules and plaques in seborrheic areas, often presenting with nail abnormalities and occasionally mucous membrane changes.It has been associated with neurocognitive/psychiatric disorders, ankylosing spondylitis, hidradenitis suppurativa and nephritis. Affected individuals also have an increased tendency to cutaneous infections. However, a thorough literature search showed no association with sensorineural hearing loss. We herein report the case of a 34-year-old Nigerian man with disfiguring Darier-White disease (DWD) associated with spondyloarthropathy and sensorineural hearing loss. We affirm that early diagnosis, prompt and appropriate therapy and adequate patient education can avert undesirable outcomes.

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来源期刊

Rwanda Medical Journal Medicine-Medicine (all)

CiteScore

0.20

自引率

0.00%

发文量

审稿时长

7 weeks

期刊介绍： The Rwanda Medical Journal (RMJ), is a Not-For-Profit scientific, medical, journal that is published entirely online in open-access electronic format. The RMJ is an interdisciplinary research journal for publication of original work in all the major health disciplines. Through a rigorous process of evaluation and peer review, The RMJ strives to publish original works of high quality for a diverse audience of healthcare professionals. The Journal seeks to deepen knowledge and advance scientific discovery to improve the quality of care of patients in Rwanda and internationally.