Darier-White病伴感觉神经性听力损失一例报告

Q4 Medicine
E. Henshaw, H. Ekpenyong, L. E. Ekafor
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引用次数: 0

摘要

Darier-White病(毛囊角化病)是一种罕见的常染色体显性遗传性皮肤病,其特征是脂溢区角化过度的丘疹和斑块,通常表现为指甲异常,偶尔还会出现粘膜变化。它与神经认知/精神疾病、强直性脊柱炎、化脓性汗炎和肾炎有关。受影响的个体也有增加皮肤感染的趋势。然而,彻底的文献检索显示,与感音神经性听力损失没有关联。我们在此报告一例34岁的尼日利亚男子,他患有与脊椎关节病和感音神经性听力损失相关的Darier-White病(DWD)。我们确认,早期诊断、及时和适当的治疗以及充分的患者教育可以避免不良结果。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Darier-White Disease with Sensorineural Hearing Loss – A Case Report
Darier-White disease (keratosis follicularis) is a rare autosomal dominant genodermatosis characterized by hyperkeratotic papules and plaques in seborrheic areas, often presenting with nail abnormalities and occasionally mucous membrane changes.It has been associated with neurocognitive/psychiatric disorders, ankylosing spondylitis, hidradenitis suppurativa and nephritis. Affected individuals also have an increased tendency to cutaneous infections. However, a thorough literature search showed no association with sensorineural hearing loss. We herein report the case of a 34-year-old Nigerian man with disfiguring Darier-White disease (DWD) associated with spondyloarthropathy and sensorineural hearing loss. We affirm that early diagnosis, prompt and appropriate therapy and adequate patient education can avert undesirable outcomes.
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来源期刊
Rwanda Medical Journal
Rwanda Medical Journal Medicine-Medicine (all)
CiteScore
0.20
自引率
0.00%
发文量
31
审稿时长
7 weeks
期刊介绍: The Rwanda Medical Journal (RMJ), is a Not-For-Profit scientific, medical, journal that is published entirely online in open-access electronic format. The RMJ is an interdisciplinary research journal for publication of original work in all the major health disciplines. Through a rigorous process of evaluation and peer review, The RMJ strives to publish original works of high quality for a diverse audience of healthcare professionals. The Journal seeks to deepen knowledge and advance scientific discovery to improve the quality of care of patients in Rwanda and internationally.
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