地理舌患者唾液Atopy生物标志物

Q4 Dentistry

European Journal of General Dentistry Pub Date : 2021-10-25 DOI:10.1055/s-0041-1736375

L. Farhad-Mollashahi, Z. Dalirsani, M. Honarmand, S. Salimi, Soudeh Shahabi Nezhad

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引用次数: 0

摘要

目的地理舌是舌背表面的粘膜炎，没有明确的病因，尽管它可能与特应性疾病有关。在这项研究中，我们评估了地理舌头患者的唾液免疫球蛋白E (IgE)和嗜酸性阳离子蛋白(ECP)水平，以研究这种疾病与过敏相关生物标志物之间的关系。材料与方法在本病例对照研究中，收集了45例地理舌患者和45例对照者的未刺激唾液，并评估了唾液IgE和ECP水平。数据分析采用SPSS 20.0，采用Mann-Whitney检验，显著性水平p < 0.05。结果病例组和对照组唾液IgE水平分别为123.76±8.1和74.34±6.2 IU/mL, ECP水平分别为9.4±6.0和7.6±3.2 ng/mL。两组患者唾液IgE (p = 0.007)和ECP (p = 0.001)水平差异有统计学意义。结论地域性舌患者唾液IgE、ECP水平增高。因此，它们可用于初步诊断检查，并调查地理舌头与过敏反应的可能联系。

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Salivary Atopy Biomarkers in Patients with Geographic Tongue

Objectives Geographic tongue is the mucositis of the dorsal surface of the tongue with no definite etiology, although it may be associated with atopic conditions. In this study, the salivary immunoglobulin E (IgE) and eosinophilic cationic protein (ECP) levels were assessed in patients with geographic tongue to examine the relationship between this condition and allergy-related biomarkers. Materials and Methods In this case-control study, unstimulated saliva was collected from 45 geographic tongue patients and 45 controls, and the salivary IgE and ECP levels were assessed. The data were analyzed with SPSS 20.0 using the Mann–Whitney test with a significance level of p < 0.05. Results The salivary IgE level in the case and control groups was 123.76 ± 8.1 and 74.34 ± 6.2 IU/mL, respectively, and the salivary ECP level was 9.4 ± 6.0 and 7.6 ± 3.2 ng/mL, respectively. There was a statistically significant difference between the two groups in terms of salivary IgE (p = 0.007) and ECP (p = 0.001) levels. Conclusion Salivary IgE and ECP levels increase in patients with geographic tongue. They can, therefore, be used for the initial diagnostic workup and to investigate the possible association of geographic tongue with allergic reactions.

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来源期刊

European Journal of General Dentistry Dentistry-Dentistry (all)

CiteScore

1.00

自引率

0.00%

发文量

期刊介绍： European Journal of General Dentistry (EJGD) is one of the leading open-access international dental journal within the field of Dentistry. The aim of EJGD is publishing novel and high-quality research papers, as well as to influence the practice of dentistry at clinician, research, industry and policy-maker level on an international basis. EJGD publishes articles on all disciplines of dentistry including the cariology, orthodontics, oral surgery, preventive dentistry, periodontology, endodontology, operative dentistry, fixed and removable prosthodontics, dental biomaterials science, long-term clinical trials including epidemiology and oral health, technology transfer of new scientific instrumentation or procedures, as well as clinically relevant oral biology and translational research.Moreover, EJGD also publish the scientific researches evaluating the use of new biomaterials, new drugs and new methods for treatment of patients with different kinds of oral and maxillofacial diseases or defects, the diagnosis of oral and maxillofacial diseases with new methods, etc. Moreover, researches on the quality of life, psychological interventions, improving disease treatment outcomes, the prevention, diagnosis and management of cancer therapeutic complications, rehabilitation, palliative and end of life care, and support teamwork for cancer care and oral health care for old patients are also welcome. EJGD publishes research articles, case reports, reviews and comparison studies evaluating materials and methods in the all fields of related to dentistry.