A. Jović, N. Vidović, D. Popović, Zorana Zlatanović, S. Cekić, D. Tiodorovic
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引用次数: 0
摘要
摘要合并痣是指在同一病变内由两种或两种以上不同类型的黑色素细胞群组成的黑素细胞病变。不同类型的合并痣可能会形成形状怪异、五颜六色的皮肤病变,使其成为最伟大的黑色素瘤模仿者之一。我们报告一位48岁的女性患者,左腰部有可疑的皮肤病变。临床上,有一个椭圆形,稍不对称的病变,尺寸为6 x 4毫米,显示多种颜色和深浅的棕色和黑色。皮肤镜检查显示,病变右侧呈棕蓝色,而病变左侧发现带毛囊周晕的精细色素网,提示诊断为合并痣。组织学检查显示真皮浅部和深层的树突状黑素细胞增殖和真皮-皮肤交界处的黑素细胞增生界限不清。为了确认皮肤镜检查结果,对肿瘤进行了手术切除。总之,皮肤镜检查有助于区分合并痣和其他黑色素细胞病变。
Dermoscopy Case of the Month Combined Nevus - a Case Report
Abstract Combined nevi are melanocytic lesions composed of two or more distinct types of melanocytic populations within the same lesion. Different types of combined nevi may form bizarrely shaped, multicolored skin lesions, making them one of the greatest melanoma mimickers. We report a 48-year-old female patient with suspicious skin lesion in the left lumbar region. Clinically, there was an oval, slightly asymmetrical lesion measuring 6 x 4 mm, showing multiple colors and shades of brown and black. A dermoscopic examination revealed a brown-bluish coloration in the right part of the lesion, while a fine pigment network with perifollicular halo was found in the left part of the lesion, suggesting the diagnosis of a combined nevus. Histological examination showed a poorly circumscribed proliferation of dendritic melanocytes in the superficial and deep dermis and proliferation of melanocytes in the dermoepidermal junction. A surgical excision of the tumor was performed, in order to confirm the dermoscopic findings. In conclusion, dermoscopy is useful in differentiating combined nevi from other melanocytic lesions.
期刊介绍:
Serbian Journal of Dermatology and Venereology is a journal of the Serbian Association of Dermatologists and Venereologists. The journal is published in English, quarterly and intended to provide rapid publication of papers in the field of dermatology and venereology. Manuscripts are welcome from all countries in the following categories: editorials, original studies, review articles, professional articles, case reports, and history of medicine.